ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (3): 187-191.doi: 10.3969/j.issn.1674-3865.2019.03.002

• 专栏 • 上一篇    下一篇

基于文献挖掘分析中医药治疗小儿癫痫的用药规律

仇明珂，王雪峰，张秀英，邱功瀚，赫昊   

  1. 110000 沈阳，辽宁中医药大学2017级中西医结合儿科学专业研究生（仇明珂）；110000 沈阳，辽宁中医药大学附属医院儿科（王雪峰，张秀英）；110000 沈阳，辽宁中医药大学研究生院（邱功瀚）；110000 沈阳，辽宁中医药大学研究生院2018级中西医结合儿科学专业研究生（赫昊）
  • 出版日期:2019-06-25 发布日期:2019-07-04
  • 通讯作者: 王雪峰，E-mail：lnzywxf@163.com
  • 作者简介:仇明珂（1994-），女，辽宁中医药大学2017级硕士研究生在读。研究方向：中医药防治儿童常见病

Analysis of the medication of traditional Chinese medicine in the treatment of children with epilepsy based on literature mining

QIU Mingke，WANG Xuefeng，ZHANG Xiuying，QIU Gonghan，HE Hao.   

  1. Liaoning University of Traditional Chinese Medicine，Shenyang 110000，China
  • Online:2019-06-25 Published:2019-07-04

PDF (PC)

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摘要： 目的
基于文献探讨近20年治疗小儿癫痫的高频中药药物及药类，在此基础上总结出小儿癫痫的用药规律，为临床治疗提供依据。
方法检索国内公开发表的中医药治疗小儿癫痫的相关文献，起止日期为2000～2019年，利用SPSS 19.0软件，采用频数分析方法。
结果文中涉及药味241味，19类中药。其中使用频率最高的为石菖蒲，为72.28%；药味以甘、辛、苦为主，累计频率达82.08%；药性以温、寒、平为主，累计频率达90.67%。归经以肝、心、脾、胃为主，累计达65.40%。所用中药种类以补虚药、平肝熄风类、化痰止咳平喘药为主，占总用药的46.90%。
结论临床治疗小儿癫痫以补益心脾、滋补肝肾、豁痰开窍、息风通络止痉为主，药物多选用甘辛苦之品。

关键词: 癫痫, 文献挖掘分析, 中医治疗, 用药规律, 儿童

Abstract: Objective
Based on the literature, to study the highfrequency traditional Chinese medicines and medicinal types for pediatric epilepsy in the recent 20 years. On this basis, to summarize the medication rules in pediatric epilepsy, which provides the basis for clinical treatment.MethodsThe related literature of traditional Chinese medicine in the treatment of childhood epilepsy published in China from 2000 to 2019 was searched. SPSS 19.0 software was used to analyze the frequency.
Results
This study involved 241 flavors and 19 kinds of traditional Chinese medicines. Among them, Acorus tatarinowii was the most frequently used(72.28%),and the flavors were mainly sweet, spicy and bitter, with a cumulative frequency of 82.08%. The medicinal properties of Acorus tatarinowii were mainly warm, cold and moderate, with a cumulative frequency of 90.67%. The main meridians were liver, heart, spleen and stomach, with a total of 65.40%. The main types of Chinese medicines used were those tonifying deficiency, calming liver and wind, resolving phlegm, relieving cough and asthma, accounting for 46.90% of the total drug use.
Conclusion
Clinical treatment for pediatric epilepsy mainly focuses on tonifying the heart and spleen, nourishing the liver and kidney, eliminating phlegm and resuscitating Qiao, relieving wind, dredging collaterals and stopping spasm. Drugs are mostly sweet, spicy and bitter.

Key words: Epilepsy, Literature mining analysis, Traditional Chinese treatment, Medication rule, Children