ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (3): 225-228.doi: 10.3969/j.issn.1674-3865.2019.03.012

• 临床护理 • 上一篇    下一篇

中西医结合内外合治儿童遗尿症疗效分析

刘小梅，李海天，张曼，闫慧敏，高杨洁，吕忠礼，沈颖   

  1. 100045 北京，国家儿童医学中心（北京）首都医科大学附属北京儿童医院综合科（刘小梅，高杨洁），康复科（李海天，张曼，吕忠礼），中医科（闫慧敏），儿童慢性肾脏病与血液净化北京市重点实验室（沈颖）
  • 出版日期:2019-06-25 发布日期:2019-07-04
  • 通讯作者: 沈颖，E-mail：shenying@bch.com.cn
  • 作者简介:刘小梅（1971-），女，医学硕士，主任医师。研究方向：小儿肾脏疾病、小儿遗尿诊治与管理
  • 基金资助:
    首都卫生发展科研专项项目（首发2016-1-2095）

Clinical observation of internal and external Treatment by traditional Chinese treatment combined with western medicine for enuresis in children

LIU Xiaomei, LI Haitian, ZHANG Man, YAN Huimin, GAO Yangjie, LYU Zhongli, SHEN Ying. Beijing Children's Hospital,   

  1. Capital Medical University, National Center for Children's Health(Beijing), Beijing 100045, China
  • Online:2019-06-25 Published:2019-07-04

PDF (PC)

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摘要： 目的
探索中西医联合内服外治疗法治疗儿童遗尿的有效性。
方法选择2016年11月至2017年12月北京儿童医院门诊接诊的7～17岁脾肾阳虚型遗尿患儿为研究对象，共67例。随机分为西医治疗组35例和中西医结合治疗组32例。西医治疗组按照国际小儿尿控协会及中国儿童单症状性夜遗尿疾病管理专家共识推荐一线治疗药物—去氨加压素口服治疗，中西医结合组在西医治疗组的基础上内服中药辅以皮肤穴位揿针贴敷法治疗，4周为1个疗程。观察两组临床疗效、中医证候改善情况和治疗期间的不良事件。
结果符合本研究入组并完成治疗及随访的63例患儿，西药治疗组32例，中西医结合组31例。中西医结合组总有效率为90.3%（28/31），西医治疗组为84.4%（27/32），两组比较差异无统计学意义（P>0.05）。中西医结合组中医证候改善好转率为96.8%（30/31），明显好于西医治疗组62.5%（20/32），差异有统计学意义（P<0.05）。两组治疗期间均未发现明显的药物相关不良反应。
结论去氨加压素联合中医辨证治疗施以中药治疗辅助穴位贴敷治疗对遗尿症儿童脾肾阳虚中医证候改善有显著疗效，可有效改善遗尿症患儿证候及体质。

关键词: 遗尿症, 中西医结合, 穴位贴敷, 儿童

Abstract: Objective
To explore the effectiveness of internal and external treatment by traditional Chinese treatment combined with western medicine for enuresis in children.
Methods
A total of 67 enuresis children(aged 7 to 17) with spleen and kidney Yang-insufficiency were chosen as the research subjects, who were treated in Beijing Children's Hospital from Nov. 2016 to Dec. 2017. They were divided into two groups according the random number table method: 35 in the western medicine treatment group and 32 in the integrated Chinese and western medicine treatment group. Both groups were treated with desmopressin(orally taken) according to the recommendations of International Pediatric Urinary Control Association and Chinese expert consensus on the management of children's single-symptom night enuresis disease. In addition, the integrated treatment group was treated with Chinese medicine(orally taken) assisted by acupuncture point paste. The treatment lasted for 4 weeks as one course. Observe the clinical effect, improvement in TCM syndromes and the adverse events during treatment in the two groups.
Results
Of the 63 children who were enrolled in the study and completed the treatment and follow-up, there were 32 in the western medicine treatment group and 31 patients in the integrated Chinese and western medicine group. The total effective rate was 90.3%(28/31) in the integrated Chinese and Western medicine group and 84.4%(27/32) in the western medicine treatment group. There was no significant difference in the effective rate between the two groups(P>0.05). The improvement rate of TCM syndromes in the integrated group was 96.8%(30/31), which was significantly better than that in the western medicine group(62.5%，20/32), and the difference was statistically significant(P<0.05). In the two groups, no significant drug-related adverse reactions were observed during the treatment.
ConclusionDesmopressin combined with TCM syndrome differentiation treatment（traditional Chinese medicine treatment combined with acupuncture point paste） has significant effect on the improvement of TCM syndromes of spleen and kidney Yang-insufficiency in children with enuresis, and can effectively improve the TCM symptoms and physique of children with enuresis.

Key words: Enuresis, Integrated Chinese and western medicine, Acupuncture point paste, Children