ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (3): 197-200.doi: 10.3969/j.issn.1674-3865.2018.03.004

• 临床论著 • 上一篇    下一篇

自拟复感汤配合捏脊疗法对反复呼吸道感染患儿唾液中分泌型IgA与血清白蛋白比值的影响

张琳，何德根，陈慧   

  1. 528400 广东 中山，中山市中医院儿科
  • 出版日期:2018-06-25 发布日期:2018-11-19
  • 通讯作者: 陈慧，Email：Syajum@163com
  • 作者简介:张琳（1978-），女，医学硕士，副主任医师。研究方向：小儿呼吸道疾患及肾病的中西医诊断与治疗
  • 基金资助:
    中山市科技局基金项目（2015B1207）

Effect on the ratio of sIgA in saliva and serum albumin in children with recurrent respiratory tract infections treated by Fugan decoction combined with chiropractic therapy

ZHANG Lin ,HE Degen，CHEN Hui   

  1. Zhongshan Hospital of Traditional Chinese Medicine，Zhongshan 528400，China
  • Online:2018-06-25 Published:2018-11-19

PDF (PC)

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摘要：
目的
观察自拟复感汤配合捏脊疗法对土虚木亢型反复呼吸道感染（RRTIs）患儿唾液中分泌型免疫球蛋白A（sIgA）与血清白蛋白（ALB）比值的影响。
方法
选择2015年12月至2016年8月中山市中医院儿科收治住院的土虚木亢型RRTIs患儿200例为研究对象，随机分为观察组和对照组各100例。因失访等原因退出或中止治疗19例，其中观察组8例，对照组11例。对照组口服匹多莫德治疗，观察组口服复感汤配合捏脊治疗，疗程1个月。治疗前和治疗3个月后检测唾液中sIgA和ALB。观察两组临床疗效。
结果
观察组总有效率为97.8%（90/92），显著高于对照组80.9%（72/89），差异有统计学意义（P<0.05）。治疗前两组sIgA/ALB水平显著低于治疗后，差异有统计学意义（P<0.05）；治疗后观察组sIgA/ALB水平显著高于对照组，差异有统计学意义（P<0.05）。
结论
复感汤配合捏脊治疗能明显提高RRTIs患儿唾液中sIgA与ALB比值，能提高患儿的黏膜免疫功能。

关键词: 反复呼吸道感染, 唾液中sIgA与血清ALB比值, 土虚木亢, 儿童

Abstract:
Objective
To observe the effect on the ratio of sIgA in saliva and serum albumin(sIgA/ALB)when Fugan decoction combined with chiropractic therapy were applied to the children with recurrent respiratory tract infections(RRTIs) with spleen deficiency and liver prosperous syndrome.
Methods
From December 2015 to August 2016，200 cases of children with RRTIs in the Department of Pediatrics admitted to Zhongshan Hospital of Traditional Chinese Medicine were selected as the subjects，and they were randomly divided into the observation group and the control group, with 100 cases in each. Nineteen cases withdrew or stopped because of missing visits, including 8 cases in the observation group and 11 cases in the control group. The control group was treated with pidotimod, while the treatment group was treated with Fugan decoction and the chiropractic therapy. Both of them were treated for one month. The sIgA and ALB in saliva were detected before treatment and 3 months after treatment，and the clinical effects of the two groups were observed.
Results
The total effective rate of the observation group was 97.8%(90/92), which was significantly higher than that of the control group(80.9%,72/89), and the difference was statistically significant(P<0.05).The level of sIgA/ALB in the two groups was significantly lower before treatment than that after treatment and the difference was statistically significant(P<0.05).The level of sIgA/ALB in the observation group was significantly higher than that of the control group after the treatment, and the difference was statistically significant(P<0.05).
Conclusion
The Fugan decoction combined with chiropractic therapy can significantly improve the ratio of sIgA/ALB and the mucosal immune function in children.

Key words: Recurrent respiratory tract infection(RRTIs), The ratio of sIgA in saliva and serum albumin(sIgA/ALB), The spleen deficiency and liver prosperous syndrome, Child