ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (5): 417-422.doi: 10.3969/j.issn.1674-3865.2018.05.015

• 临床论著 • 上一篇    下一篇

中成药口服治疗小儿轮状病毒肠炎随机对照试验的系统评价

徐万超，薛征，刘亚尊，宋辰斐   

  1. 200071 上海，上海中医药大学附属市中医医院儿科
  • 出版日期:2018-10-25 发布日期:2018-12-03
  • 通讯作者: 薛征，E-mail：shszyyyek@126.com
  • 作者简介:徐万超(1991-)，男，2018级上海中医药大学中医儿科学博士研究生在读。研究方向：小儿肺系、脾系疾病的诊治
  • 基金资助:
    上海市进一步加快中医药事业发展三年行动计划(2014-2016)建设项目(ZY3-LCPT-1005)

Systematic review of randomized controlled trials of Chinese traditional patent medicine orally taken in the treatment of rotavirus enteritis in children

XU Wanchao，XUE Zheng，LIU Yazun，SONG Chenfei   

  1. Shanghai Municipal Hospital of Traditional Chinese Medicine，Shanghai 200071，China
  • Online:2018-10-25 Published:2018-12-03

PDF (PC)

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摘要：
目的
评价中成药口服治疗小儿秋季腹泻疗效与安全性。
方法
计算机检索中国期刊全文数据库(CNKI)、维普数据库(VIP)、中国生物医学文献数据库(CBM)、万方全文数据库、中国优秀博硕士学位论文全文数据库(CMFD)、Pubmed、COCHRANE图书馆、Clinical Trial有关中成药口服治疗小儿秋季腹泻的随机对照试验，纳入研究的质量评价与资料提取由两名工作人员独立完成，运用Revman5.3软件进行分析评价。
结果
最终纳入17个随机对照试验文献，治疗组为1 043例，对照组947例，共1 990例，结局指标中治疗组在有效率、轮状病毒转阴率、止泻时间均优于对照组，由于纳入文献质量较低，故不予合并，只做描述性分析。
结论
中成药口服治疗小儿秋季腹泻具有一定的有效率，需更高质量证据文献进一步验证。

关键词: 轮状病毒腹泻, 中成药, 系统评价, 儿童

Abstract:
Objective
To assess the efficacy and safety of Chinese medicine for infantile autumn diarrhe.
Methods
An extensive search was carried out in the databases， including CNKI,VIP,CBM,Wanfang fulltext database,CMFD,Pubmed,COCHRANE library and Clinical Trial, for  randomized controlled trials about oral administration of Chinese medicine for the treatment of infantile diarrhea. The quality evaluation and data extraction of the included researches were completed independently by two staff members. Revman5.3 software was used for analysis and evaluation.
Results
Totally 17 RCT literatures were included,1 990  cases in total,1 043 in the treatment group and 947 in the control group.Of the outcome indexes, the effective rate, the rotavirus conversion rate and the time of stopping diarrhea were better in the treatment group than in the control group. Because of the low quality of the literature, we didn't combine them, and only did descriptive analysis.
Conclusion
Oral administration of Chinese medicine for the treatment of children's autumn diarrhea has a certain effect. But higher quality evidence is needed for further verification.

Key words: Rotavirus diarrhea, Chinese traditional patent medicine, Systematic review, Child