ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (5): 433-436.doi: 10.3969/j.issn.1674-3865.2018.05.019

• 临床研究 • 上一篇    下一篇

消斑汤联合西医治疗儿童过敏性紫癜疗效观察

李维丽，牛玉红   

  1. 462000 河南 漯河，漯河市第三人民医院儿科
  • 出版日期:2018-10-25 发布日期:2018-12-03
  • 作者简介:李维丽(1983-)，女，主治医师。研究方向：儿童肾脏疾病的防治，E-mail:djhshenkai@126.com

Effect of Xiaoban decoction combined with western medicine on allergic purpura in children

LI Weili，NIU Yuhong   

  1. Department of Paediatrics, Luohe Third People's Hospital, Luohe 462000, China
  • Online:2018-10-25 Published:2018-12-03

PDF (PC)

127

摘要：
目的
探讨消斑汤联合西医治疗儿童过敏性紫癜的疗效。
方法
选取2014年5月至2017年5月漯河市第三人民医院儿科收治的过敏性紫癜患儿68例为研究对象，随机分为对照组和观察组各34例。对照组给予常规西医治疗，观察组在对照组基础上给予消斑汤治疗，观察两组临床疗效、凝血功能指标和临床主要症状体征改善情况。
结果
观察组临床总有效率为97.06%(33/34)，显著高于对照组73.53%(25/34)，差异有统计学意义(P<0.05)。观察组皮疹、腹痛、关节肿痛及血尿消失时间显著短于对照组，差异有统计学意义(P<0.05)。观察组治疗后凝血功能指标凝血酶原时间、凝血活酶时间水平显著高于对照组，纤维蛋白原水平显著低于对照组，差异有统计学意义(P<0.05)。两组均未发生明显不良反应。
结论
消斑汤联合西医治疗儿童过敏性紫癜疗效及止血效果显著，可快速改善患儿相关症状，临床应用安全性高。

关键词: 过敏性紫癜, 消斑汤, 中西医治疗, 儿童

Abstract:
Objective
To explore the effect of Xiaoban decoction combined with western medicine on allergic purpura in children.
Methods
A total of 68 children with allergic purpura were randomly divided into control group(34 cases) and observation group(34 cases). Both groups were given conventional western medicine; besides, the observation group was given additional Xiaoban decoction. The curative effects coagulation indexes and improvement in the main symptoms and signs of the two groups were observed and compared.
Results
The total effective rate in the observation group was 97.06%(33/34),which was significantly higher than that in the control group(73.53%,25/34,P<0.05). The disappearance time of rash, abdominal pain, joint swelling and pain, and hematuria in the observation group was significantly shorter than that in the control group(P<0.05). After treatment, the PT and APTT levels in the observation group were significantly higher than those in the control group, while the level of FIB was lower(P<0.05). There was no obvious adverse reactions in the two groups.
ConclusionXiaoban decoction combined with western medicine has significant curative and hemostatic effects for children with allergic purpura, which can quickly improve the related symptoms of children and is with high safety.

Key words: Allergic purpura, Xiaoban decoction, Integrated traditional and western medicine, Children