ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (2): 96-100.doi: 10.3969/j.issn.1674-3865.2019.02.002

• 专栏 • 上一篇    下一篇

广西地区特禀质儿童肺炎易患因素分析

周志宁，李洁，姚勇志，王力宁，李志锋，蒙春雪，杨黎明，蔡晓静，莫雪莹，黎丽，#br# 黄志碧，张晓春，孙继超，梁廷君，苏文静   

  1. 530023 南宁，广西中医药大学第一临床医学院2016级中医儿科专业研究生(周志宁，李洁，梁廷君，苏文静)；广西中医药大学第一附属医院儿科(姚勇志，王力宁，李志锋，张晓春，孙继超)；545000 广西 柳州，柳州市妇幼保健院中医科(蒙春雪)；543200 广西 岑溪，岑溪市中医医院儿科(杨黎明)；536000 广西 北海，北海市中医医院儿科(蔡晓静，莫雪莹，黎丽)；530023 南宁，广西医科大学基础医学院教研室(黄志碧)
  • 出版日期:2019-04-25 发布日期:2019-05-08
  • 通讯作者: 王力宁，E-mail：wln21@126.com
  • 作者简介:周志宁(1992-)，女，广西中医药大学第一临床医学院2016级硕士研究生在读。研究方向：哮喘与肺系疾病的防治
  • 基金资助:
    国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2015040)；广西名中医民族医传承工作室建设项目(桂卫中［2013］10号)

Analysis of the risk factors of pneumonia in intrinsic-quality children in Guangxi

ZHOU Zhining，LI Jie， YAO Yongzhi，WANG Lining，LI Zhifeng，MENG Chunxue，YANG Liming，CAI Xiaojing，MO Xueying，LI Li，HUANG Zhibi，ZHANG Xiaochun，SUN Jichao，LIANG Tingjun，SU Wenjing   

  1. The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530023，China
  • Online:2019-04-25 Published:2019-05-08

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摘要：

目的
探讨广西地区特禀质儿童社区获得性肺炎（CAP)的易患因素，为特禀质儿童社区获得性肺炎的防治提供临床循证依据。
方法
采用问卷调查的方法，于2017年4月至2018年9月在岑溪市、柳州市、北海市、三江县及南宁市招募1～6岁的儿童进行调查问卷。以既往是否患CAP作为因变量，以被调查的特禀质儿童的39个可能与CAP的易患因素及体质类型作为自变量，对特禀质儿童组的CAP相关易感因素进行逐步Logistic回归分析。
结果
调查收集的有效问卷共466份，其中343例为特禀质，兼积热质104例，兼气虚质66例，兼阴虚质38例，兼痰湿质16例，兼阳虚质13例。343例特禀质儿童，既往有患CAP病史者214例(62.4%)，无CAP病史的129例(37.6%)；非特禀质123例，其中有CAP病史38例(30.9%)，无CAP病史85例(69.1%)；经逐步Logistic回归分析发现，特禀质儿童CAP与既往有哮喘、反复呼吸道感染、营养不良等基础疾病、既往住院史及抗生素的使用差异有统计学意义(P<0.05)；特禀质儿童患CAP的次数与特禀质兼痰湿质有关。
结论
特禀质儿童与CAP可能有密切相关性；既往有哮喘、反复呼吸道感染、营养不良基础病以及抗生素药物使用是特禀质儿童CAP易患因素；特禀质合并痰湿质的儿童患CAP的次数高于其他体质类型儿童。

关键词: 肺炎, 特禀质, 易患因素, 回归分析, 儿童

Abstract:
Objective
To study the risk factors of community-acquired pneumonia(CAP) in intrinsic-quality children in Guangxi in order to provide clinical evidence-based basis for its prevention and treatment.
Methods
A questionnaire survey was performed in the children aged one to six years in the cities of Chenxi, Liuzhou, Beihai and Nanning as well as in Sanjiang county from April 2017 to September 2018.The dependent variable was whether the children had had CAP before, and the independent variable is the 39 possibilities of the intrinsic-quality children, the risk factors of CAP and the constitute type. The gradual Logistic regression analysis was made on the CAPrelated risk factors in these children.
Results
A total of 466 valid questionnaires were collected, among which there were 343 cases of intrinsic quality,104 cases combined with accumulation of heat, 66 cases with qi-deficiency, 38 with yin-deficiency,16 with phlegm-dampness, and 13 with yang-deficiency. In the 343 children,214(62.4%) had had CAP，129(37.6%) had had no CAP; in the 123 children with nonintrinsicquailty,38 had had CAP(30.9%),85 had had no CAP(69.1%), the gradual Logistic regression analysis showed that there was statistically significant relationship between intrinsicquality children with CAP and the following factors: history of asthma，recurrent respiratory tract infection, the basic diseases such as malnutrition, hospitalization history and use of antibiotics(P<0.05);the incidence of CAP in the intrinsic-quality children was  related to intrinsic quality combined with phlegm-dampness.
Conclusion
There may be close relationship between intrinsic quality and CAP in children; the risk factors of CAP in these children are：combination with asthma, recurrent respiratory tract infection, malnutrition and other basic diseases, and use of antibiotics; the incidence of CAP is higher in the children combined with phlegm-dampness than in those with other constitutions.

Key words: Pneumonia, Intrinsic quality, Risk factors, Regression analysis, Child