ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (4): 295-300.doi: 10.3969/j.issn.1674-3865.2019.04.007

• 临床论著 • 上一篇    下一篇

儿童支气管哮喘缓解期中医药治疗Meta分析

徐婧,李建保,王霞,陈迪   

  1. 610072 成都,成都中医药大学2017级中医儿科学专业研究生(徐婧,王霞,陈迪);成都中医药大学儿科教研室(李建保)
  • 出版日期:2019-08-25 发布日期:2019-09-18
  • 通讯作者: 李建保,E-mail:leeshichen@outloo.com
  • 作者简介:徐婧(1993-),女,成都中医药大学2017级硕士研究生在读。研究方向:儿童肺系疾病的诊治

Meta-analysis of TCM therapy for children with bronchial asthma at remission stage

XU Jing,LI Jianbao,WANG Xia,CHEN Di   

  1. Chengdu University of TCM,Chengdu 610072,China
  • Online:2019-08-25 Published:2019-09-18

摘要:
目的
系统评价单纯中药治疗儿童支气管哮喘缓解期的临床疗效和安全性。
方法
计算机检索中国万方数据,检索的时间范围是自2006年1月到2019年2月,纳入所有单纯中药治疗儿童支气管哮喘缓解期的随机对照试验。由两位研究者独立筛选文献、提取资料和评价纳入研究的偏倚风险后,采用RevMan 5.3软件进行Meta分析。
结果
最终纳入29个研究,共2487例患者。Meta分析结果显示,相比单纯西药治疗,纯中医治疗能显著提高儿童支气管哮喘缓解期的临床有效率[OR=3.09,95% CI(2.42,3.94),P<0.000 01],单项症状控制率也优于对照组[OR=14.07,95%CI(6.99,2831),P<0.000 01],其差异均具有统计学意义。
结论
本研究结果显示中药在临床有效性方面较单纯西药治疗有一定的优势。

关键词: 哮喘缓解期, 中医治疗, 随机对照试验, Meta分析, 儿童

Abstract:
Objective
To systematically evaluate the therapeutic effect and safety of traditional Chinese medicine in the treatment of children with bronchial asthma at remission stage.
Methods
 We searched CNKI to collect randomized controlled trials(RCTs) on traditional Chinese medicine in the treatment of children with bronchial asthma at remission stage from January to February 2019.Two reviewers independently screened literature, extracted data and assessed the risk of bias of included studies. After that a Metaanalysis was made by using RevMan 5.3 software.
Results 
A total of 29 RCTs involving 2 487 patients were included in the study. The Metaanalysis results showed that compared with western medicine, the traditional Chinese medicine could significantly improve the clinical efficiency[OR=3.09,95%CI(2.42,3.94), P<0.000 01],and the control rate of individual symptom was better than the control group[OR=14.07,95%CI(6.99,28.31),P<0.000 01], there being statistically significant differences.
Conclusion
This study shows that the traditional Chinese medicine is superior to western medicine in overall clinical efficacy.