ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (4): 311-314.doi: 10.3969/j.issn.1674-3865.2019.04.010

• 临床研究 • 上一篇    下一篇

中西医结合治疗儿童慢性鼻-鼻窦炎临床观察

孙嘉蔚,冷辉   

  1. 110000 沈阳，辽宁中医药大学2017级中西医结合临床(耳鼻喉)专业研究生(孙嘉蔚)；辽宁中医药大学附属医院耳鼻咽喉科(冷辉)
  • 出版日期:2019-08-25 发布日期:2019-09-18
  • 通讯作者: 冷辉，E-mail：lengh1976@16.com
  • 作者简介:孙嘉蔚(1993-)，女，辽宁中医药大学2017级硕士研究生在读。研究方向：耳鼻咽喉病的中西医结合基础和临床治疗

Clinical observation on the treatment of chronic rhinosinusitis in children by integrated traditional Chinese and western medicine

SUN Jiawei，LENG Hui   

  1. Liaoning University Of Traditional Chinese Medicine，Affiliated Hospital of Liaoning University of Traditional Chinese Medicine，Shenyang 110000，China
  • Online:2019-08-25 Published:2019-09-18

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摘要：
目的
对通窍方联合欧龙马滴剂治疗小儿慢性鼻-鼻窦炎肺脾气虚证的临床疗效进行观察。
方法
选取2017年9月至2018年9月辽宁中医药大学附属医院耳鼻咽喉科就诊的慢性鼻窦炎患儿80例为研究对象，随机分为对照组和观察组各40例。对照组使用欧龙马滴剂口服联合辅舒良鼻喷雾剂喷鼻治疗，观察组在对照组的基础上联合通窍方中药汤剂口服治疗，疗程均为1个月。观察两组患儿治疗后主要症状改善情况及疗效，随访3个月观察复发情况及不良反应。
结果
治疗1个月后，观察组对鼻塞和流涕症状改善显著好于对照组，差异均有统计学意义(P<0.05)；两组对头痛和嗅觉减退症状改善相比差异无统计学意义(P>0.05)。观察组总有效率为92.5%(37/40)，显著高于对照组70.0%(28/40)，差异有统计学意义(P<0.05。随访3个月，观察组复发率为5.0%(2/40)，显著低于对照组22.5%(9/40)，差异有统计学意义(P<0.05)。两组患儿治疗期间均未出现明显不良反应。
结论
通窍方联合欧龙马滴剂及辅舒良鼻喷雾剂治疗小儿慢性鼻-鼻窦炎肺脾气虚证的疗效优于单纯西医治疗，临床应积极推广该中西医结合治疗方案。

关键词: 慢性鼻-鼻窦炎, 中西医结合治疗, 通窍方, 欧龙马滴剂, 辅舒良鼻喷雾剂, 儿童

Abstract:
Objective
To observe the clinical efficacy of Tongqiao decoction combined with Sinupret drops in the treatment of chronic rhinosinusitis with spleen-qi deficiency syndrome in children.
Methods
Eighty children with chronic rhino sinusitis who were admitted to the Department of Otorhinolaryngology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, from September 2017 to September 2018, were enrolled in the study. They were randomly divided into control group(40 children) and observation group(40 children). The control group was treated with Sinupret drops(Oral) combined with Fluticasone Propionated Nasal Spray for nasal spray. The observation group was treated with Tongqiao decoction(Chinese herbal decoction) on the basis of the treatment for control group. The course of treatment was 1 month. The improvement of the main symptoms and the curative effect of the two groups were observed. The recurrence and adverse reactions were observed during the 3 months of follow-up.
Results
After 1 month of treatment, the improvement in nasal congestion and runningnose symptoms in the observation group was significantly better than that in the control group, and the difference was statistically significant(P<0.05). There was no significant difference between the two groups in the improvement of headache or hyposmia symptoms(P>0.05). The total effective rate of the observation group was 92.5%(37/40), which was significantly higher than that of the control group(70.0%, 28/40). The difference was statistically significant(P<0.05). After 3 months of follow-up, the recurrence rate of the observation group was 5.0%(2/40), which was significantly lower than that of the control group(22.5%,9/40). The difference was statistically significant (P<0.05). There were no significant adverse reactions during the treatment period in both groups.
Conclusion
Tongqiao decoction combined with Sinupret drops and Fluticasone Propionated Nasal Spray is better than pure western medicine in treating children with chronic rhinosinusitis with spleen-qi deficiency syndrome. Clinically, this combination of Chinese and western medicine should be actively promoted.

Key words: Chronic rhinosinusitis, Combination treatment of traditional Chinese and western medicine, Tongqiao prescription, Sinupret drops, Fluticasone Propionated Nasal Spray, Children