ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (5): 426-428.doi: 10.3969/j.issn.1674-3865.2019.05.015

• 临床研究 • 上一篇    下一篇

小儿肺炎支原体感染临床检验的诊断价值

尚燕   

  1. 450000 郑州,郑州大学附属儿童医院、河南省儿童医院、郑州儿童医院检验科
  • 出版日期:2019-11-01 发布日期:2019-11-08
  • 作者简介:尚燕(1986-),女,医学硕士,检验师。研究方向:临床常规检验,E-mail:shangyan0626@163.com

Diagnostic value of clinical testing for children with Mycoplasma pneumoniae infection

SHANG Yan   

  1. Children's Hospital Affiliated to Zhengzhou University; Henan Children's Hospital; Zhengzhou Children's Hospital,Zhengzhou 450000,China
  • Online:2019-11-01 Published:2019-11-08

摘要:
目的
探究在治疗小儿肺炎支原体感染中临床检验的诊断价值。
方法
选择2017年3月至2018年11月郑州大学附属儿童医院收治的肺炎支原体感染患儿90例作为观察组,同期选取我院健康检查儿童90例为对照组,采集两组儿童的血液以检测其血清免疫球蛋白、红细胞免疫情况及外周T淋巴细胞亚群,并将结果进行分析比对。
结果
两组IgG水平比较差异无统计学意义(P>0.05);观察组IgM水平显著高于对照组,IgA水平显著低于对照组,差异有统计学意义(P<0.05)。观察组RBCICR、免疫黏附促进因子、RBC-C3bR显著低于对照组,免疫黏附抑制分子显著高于对照组,差异有统计学意义(P<0.05)。观察组CD3+、CD4+、CD4+/CD8+显著低于对照组,CD8+显著高于对照组,差异有统计学意义(P<0.05)。
结论
在小儿肺炎支原体感染中患儿的免疫功能受到影响,患儿的血清免疫球蛋白、红细胞免疫情况以及外周血T淋巴细胞状态与健康儿童相比较低,因此在治疗过程中应注意患儿免疫功能的情况。

关键词: 肺炎支原体感染, 血清免疫球蛋白, 红细胞免疫, 外周血T淋巴细胞亚群, 儿童

Abstract:
Objective
To explore the diagnostic value of clinical testing in the treatment of children with Mycoplasma pneumoniae infection.
Methods
A total of 90 children with Mycoplasma pneumoniae infection admitted to the Children's Hospital of Zhengzhou University from March 2017 to November 2018 were selected as observation group. Meanwhile,90 children receiving health examination in our hospital were selected as the control group. The blood of the two groups of children was collected for testing. The serum immunoglobulin, erythrocyte immune status and peripheral T lymphocyte subsets were analyzed and compared.
Results
There was no significant difference in IgG levels between the two groups(P>0.05). The level of IgM in the observation group was significantly higher than that in the control group, while the level of IgA was significantly lower, the difference being statistically significant(P<0.05). The RBCICR, immune adhesion promoting factor and RBC-C3bR in the observation group were significantly lower than those in the control group, while the immunoadhesive inhibitory molecules were significantly higher, the difference being statistically significant(P<0.05). CD3+, CD4+ and CD4+/CD8+ in the observation group were significantly lower than those in the control group, while CD8+ was significantly higher, and the difference was statistically significant(P<0.05).
Conclusion
The immune function of the children with Mycoplasma pneumoniae infection is affected. The serum immunoglobulin, erythrocyte immune status and peripheral blood T lymphocyte status of these children are lower than those of healthy children. Therefore, the children's immune function should be paid attention to during treatment.

Key words: Mycoplasma pneumoniae infection, Serum immunoglobulin, Erythrocyte immunity, Peripheral blood T lymphocyte subsets, Children