ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (5): 433-436.doi: 10.3969/j.issn.1674-3865.2020.05.018

• 临床研究 • 上一篇    下一篇

益气健脾防感汤辅助治疗小儿反复呼吸道感染症的临床疗效观察

王紫洁   

  1. 410000 长沙,湖南省儿童医院药学部
  • 出版日期:2020-10-25 发布日期:2020-11-28
  • 通讯作者: 王紫洁,E-mail:34245761652@qq.com
  • 作者简介:王紫洁(1990-),女,药师。研究方向:儿童静脉药物配置和合理用药

Clinical observation on Yiqi Jianpi Fanggan decoction in auxiliary treatment of recurrent respiratory tract infection in children

  • Online:2020-10-25 Published:2020-11-28

摘要: 目的 探讨常规西药、益气健脾防感汤联合方案用于小儿反复呼吸道感染(RRTI)临床治疗的效果。 方法 选取2018年2月至2019年6月在本院诊治的RRTI患儿82例按治疗方式分为两组,接受常规西药治疗40例患儿作为对照组,接受西药+益气健脾防感汤治疗42例患儿作为观察组。回顾分析患儿中医证候积分、症状消失时间、免疫功能改善等情况。 结果 观察组治疗后相关中医证候积分均显著低于对照组,差异有统计学意义(P<0.05)。观察组临床治疗总有效率92.9%(39/42),高于对照组75.0%(30/40),差异有统计学意义(P<0.05)。观察组患儿退热、咳嗽消失、眼部充血消失时间均显著低于对照组,差异有统计学意义(P<0.05)。观察组治疗后CD3+、CD4+水平均显著高于对照组,CD8+水平显著低于对照组,差异有统计学意义(P<0.05)。 结论 在常规西药治疗基础上再给予RRTI患儿益气健脾防感汤治疗,可明显提高临床症状改善效果及总疗效,有效增强机体免疫功能。

关键词: 小儿反复呼吸道感染, 益气健脾防感汤, 症状, 中医证候积分, 免疫功能

Abstract: Objective To evaluate the clinical effect of routine western medicine combined with Yiqi Jianpi Fanggan decoction in the treatment of repeated respiratory tract infection in children. Methods The 82 children with recurrent respiratory tract infection who were treated in our hospital from February 2018 to June 2019 were divided into two groups based on treatment methods,40 children treated with conventional western medicine were included as control group, and 42 children treated with western medicine plus Yiqi Jianpi Fanggan decoction as observation group. The TCM syndrome score, time of symptom relief and improvement in immune function were analyzed retrospectively. Results The TCM syndrome scores of the observation group after treatment were significantly lower than those of the control group(P<0.05).The total effective rate was 92.86%(39/42) in observation group, which was significantly higher than that in control group(75.00%,30/40)(P<0.05).The time in the relief of fever, cough and red eyes was significantly shorter in the observation group than in the control group(P<0.05).CD8+ in the observation group was significantly lower than in the control group, and CD3+ and CD4+ in the observation group were significantly higher than in the control group(P<0.05). Conclusion On the basis of conventional western medicine, Yiqi Jianpi Fanggan decoction can obviously improve the effect of relieving clinical symptoms and the total curative effect, and effectively enhance the immunity function of the body.

Key words: Repeated respiratory tract infection in children, Yiqi Jianpi Fanggan decoction, Symptoms, Integral Calculus of TCM Syndrome, Immune function