ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (4): 304-307.doi: 10.3969/j.issn.1674-3865.2018.04.009

• 临床研究 • 上一篇    下一篇

参赭镇气汤治疗小儿多发性抽动症临床疗效观察

宋淑萍   

  1. 743011 甘肃 定西,定西市安定区第二人民医院儿科
  • 出版日期:2018-08-25 发布日期:2018-12-03
  • 作者简介:宋淑萍(1975-),女,副主任医师。研究方向:儿科常见疾病的中西医结合治疗,E-mail:1462897002@qq.com

Observation on the clinical effect of Shenzhe Zhenqi decoction in the treatment of children with multiple tic disorder

SONG Shuping   

  1. Department of Pediatrics, the Second People's Hospital of Anding District, Dingxi 743011,China
  • Online:2018-08-25 Published:2018-12-03

摘要:
目的
观察参赭镇气汤治疗小儿多发性抽动症的临床疗效。
方法
2014年9月至2016年10月定西市安定区第二人民医院儿科收治的多发性抽动症患儿60例为研究对象,随机分为观察组和对照组各30例。观察组采用参赭镇气汤加味治疗,对照组采用口服氟哌啶醇,有椎体外系副作用时配合安坦治疗。两组均治疗1个疗程。观察临床疗效、副作用发生率、中医证候治疗效果及远期预后情况。
结果
观察组临床总有效率为86.7%(26/30)与对照组83.3%(25/30)比较差异无统计学意义(P>0.05)。治疗后观察组副作用发生率为0,显著低于对照组40%(12/30),差异有统计学意义(P<0.01)。观察组中医证候有效率为1000%(30/30),显著优于对照组36.7%(11/30),差异有统计学意义(P<0.05)。两组患儿半年内复查,观察组无一例复发,对照组有2例因受情绪刺激后复发,复发率为6.7%(2/30)。
结论
参赭镇气汤加味治疗小儿多发性抽动症有较好疗效,从肝、肾、脾、肺等多方面调治,恢复脏腑的功能,其疗效与西药相当,临床值得推广。

关键词: 多发性抽动症, 参赭镇气汤, 氟哌啶醇, 儿童

Abstract:
Objective:
To observe the clinical efficacy of Shenzhe Zhenqi decoction in the treatment of children with multiple tic disorder.
Methods:
From September 2014 to October 2016, 60 children with multiple tic disorder were admitted to the Pediatric Department of the Second People's Hospital of Anding District, Dingxi City for treatment, and they were randomly divided into observation group and control group(30 in each). The observation group was treated with Shenzhe Zhenqi decoction; the control group was treated with oral haloperidol, and Antan was used when there are side effects of vertebral body. Both groups were treated for 1 course of treatment. Observe the clinical efficacy, the incidence of side effects, the therapeutic effect on TCM syndromes and the long-term prognosis.
Results:
There was no significant difference in the total effective rate between the observation group(86.7%,26/30) and the control group(83.3%,25/30)(P>0.05). After treatment, the incidence of side effects in the observation group was 0, which was significantly lower than that in the control group (40%,12/30), and the difference was statistically significant(P<0.01). The effective rate of TCM syndromes in the observation group was 100.0% (30/30), which was significantly better than that in the control group (36.7%,11/30). The difference was statistically significant (P<0.05). Two groups of children were reexamined within half a year, and there was no recurrence in the observation group, but two patients in the control group relapsed after emotional stimulation, and the recurrence rate was 6.7%(2/30).
Conclusion:Shenzhe Zhenqi decoction has a good curative effect on children with multiple tic disorder. The treatment can be performed from liver, kidney, spleen and lung to restore the function of viscera. Its curative effect is comparable to that of western medicine, and its clinical value is worth promoting.

Key words: Multiple tic disorder, Shenzhe Zhenqi decoction, Haloperidol, Children