ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (4): 317-319.doi: 10.3969/j.issn.1674-3865.2018.04.013

• 临床研究 • 上一篇    下一篇

中药保留灌肠联合地西泮治疗小儿热性惊厥疗效观察

刘正茂   

  1. 441000 湖北 襄阳，襄阳市中医医院儿科
  • 出版日期:2018-08-25 发布日期:2018-12-03
  • 作者简介:刘正茂（1983-），男，医学硕士，医师。研究方向：中西医结合治疗小儿呼吸系统和消化系统疾病，E-mail：finding12@163.com

Effect of Chinese medicine retention enema combined with diazepam in treatment of febrile convulsion in children

LIU Zhengmao   

  1. Department of Pediatrics, Xiangyang Hospital of Traditional Chinese Medicine, Xiangyang 441000,China
  • Online:2018-08-25 Published:2018-12-03

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摘要：
目的
观察中药保留灌肠联合地西泮静脉注射治疗小儿热性惊厥的疗效。
方法
选择2015年9月至2017年9月襄阳市中医医院儿科收治的热性惊厥患儿65例为研究对象，随机分为观察组42例和对照组23例。观察组采用中药保留灌肠及静脉注射地西泮，对照组采用静脉注射地西泮和双氯芬酸钠直肠给药，根据患儿病情轻重治疗3～5 d。观察两组临床总有效率及72 h惊厥再发率。
结果
观察组总有效率为97.6%（41/42），显著高于对照组73.9%（17/23），差异有统计学意义（P<0.05）。观察组患儿72 h惊厥再发率为2.4%（1/42），显著低于对照组26.1%（6/23），差异有统计学意义（P<0.05）。
结论
中药保留灌肠联合地西泮静脉注射治疗小儿热性惊厥疗效，优于静脉注射地西泮和双氯芬酸钠直肠给药，且再发率低。

关键词: 热性惊厥, 中药治疗, 直肠给药, 儿童

Abstract:
Objective:
To observe the curative effect of intravenous injection of diazepam combined with Chinese medicine retention enema in the treatment of febrile convulsion in children.
Methods:
A total of 65 children with febrile seizures admitted from September 2015 to September 2017 to Xiangyang Hospital of Traditional Chinese Medicine were selected and randomly divided into two groups: 42 cases in the observation group and 23 cases in the control group. The observation group was treated by the intravenous injection of diazepam and Chinese medicine retention enema, and the control group was given intravenous injection of diazepam and rectal administration of diclofenac sodium. The patients were treated for 3 to 5 days according to the severity of the disease. The total effective rate of the two groups and the recurrence rate of convulsion within 72h were observed.
Results:
The total effective rate in the observation group(97.6%,41/42) was significantly higher than that in the control group(73.9%,17/23)(P<0.05), and the recurrence rate within 72h in the observation group(2.4%,1/42) was lower than that in the control group(26.1%,6/23)(P<0.05).
Conclusion:The effectiveness of intravenous injection of diazepam combined with Chinese medicine retention enema is better than that of intravenous injection of diazepam combined with rectal administration of diclofenac sodium, and the recurrence rate is low.

Key words: Febrile convulsion, Chinese medicine treatment, Rectal administration, Children