ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (5): 439-441.doi: 10.3969/j.issn.1674-3865.2018.05.021

• 临床研究 • 上一篇    下一篇

喜炎平注射液治疗小儿病毒性脑炎临床观察

胡凤阳   

  1. 110034 沈阳,沈阳市儿童医院内五病房
  • 出版日期:2018-10-25 发布日期:2018-12-03
  • 作者简介:胡凤阳(1983-),女,主治医师。研究方向:小儿呼吸系统和神经系统疾病的诊治,E-mail:3479499846@qq.com

Clinical observation on Xiyanping injection in the treatment of children with viral encephalitis

HU Fengyang   

  1. Shenyang Children's Hospital,Shenyang 110034,China  
  • Online:2018-10-25 Published:2018-12-03

摘要:
目的
探讨喜炎平注射液在小儿病毒性脑炎临床治疗中的应用效果。
方法
2015年3月至2017年4月沈阳市儿童医院收治住院的小儿病毒性脑炎患儿94例,随机分为观察组和对照组各47例。观察组使用喜炎平注射液进行抗病毒治疗,对照组使用利巴韦林进行抗病毒治疗,用药1周观察两组患儿临床治疗效果及其临床症状体征改善情况、不良反应情况。
结果
观察组患儿治疗总有效率为95.74%(45/47),显著高于对照组80.85%(38/47),差异有统计学意义(P<0.05)。观察组意识恢复时间、退热时间、头痛呕吐消失时间均短于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为2.13%(1/47),显著低于对照组21.3%(10/47),差异有统计学意义(P<0.05)。
结论
在小儿病毒性脑炎临床治疗中,喜炎平注射液是一种安全、可靠的治疗药物,能够快速、有效的解除患儿的病痛,更好的保障其健康安全。

关键词: 病毒性脑炎, 喜炎平注射液, 儿童

Abstract:
Objective
To explore the clinical effect of Xiyanping injection in the treatment of children with viral encephalitis.
Methods
A total of 94 children who were treated for viral encephalitis in Shenyang Children's Hospital from March 2015 to April 2017 were randomly divided into two groups: observation(47 cases) and control group(47 cases). The observation group was given Xiyangping injection for antiviral treatment, and the control group received ribavirin. After one week of treatment, the clinical effect, the improvement in clinical symptoms and signs, and the incidence of adverse reactions were observed in the two groups.
Results
The total effective rate of observation group was 95.74%(45/47),significantly higher than that of the control group(80.85%,38/47)(P<0.05). The consciousness recovery time, antipyretic time and the time of headache and vomiting disappearance were shorter in the observation group, and there was statistical difference(P<0.05). The incidence rate of adverse reactions was 2.13%(1/47) in the observation group, which was significantly lower than that in the control group(21.3%,10/47) ﹙P<0.05﹚.
ConclusionIn the treatment of children with viral encephalitis, Xiyanping injection is safe and reliable, which has quick and significant effect on the disease, safeguarding the health of children better.

Key words: Viral encephalitis, Xiyanping injection, Child