ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (3): 233-235.doi: 10.3969/j.issn.1674-3865.2017.03.016

• 临床研究 • 上一篇    下一篇

硒酵母结合常规疗法治疗儿童慢性感染性腹泻临床疗效分析

牟纲，罗如平   

  1. 410007 长沙，湖南省儿童医院感染科
  • 出版日期:2017-06-25 发布日期:2017-12-08
  • 通讯作者: 牟纲，E-mail:hongyongx@126.com
  • 作者简介:牟纲（1977-），男，主治医师。研究方向：儿童感染性疾病的诊治

Clinical effects analysis of selenium yeast combined with conventional therapy in treatment of children with chronic infectious diarrhea

MU Gang，LUO Ruping   

  1. Department of Infection, Hunan Children's Hospital, Changsha 410007,China
  • Online:2017-06-25 Published:2017-12-08

PDF (PC)

113

摘要：
目的
探讨硒酵母治疗儿童慢性感染性腹泻的临床疗效。
方法
2015年1月至2016年7月湖南省儿童医院感染科收治住院的慢性感染性腹泻患儿56例，随机分为观察组和对照组各28例。对照组给予调整饮食、保护胃肠黏膜、口服补液盐Ⅲ常规治疗；观察组在对照组治疗基础上口服硒酵母混悬液，疗程均14 d。比较两组患儿排便频率和粪便性状。
结果
观察组患儿自服药第6天至疗程结束，观察组排便正常率均高于对照组，差异有统计学意义（P<0.05）。观察组患儿自服药第6天至疗程结束，观察组粪便性状正常率均高于对照组，差异有统计学意义（P<0.05）。未发现因口服硒酵母而引起的不良反应。
结论
硒酵母治疗小儿感染性腹泻效果好，且无明显不良反应，值得临床推广应用。

关键词: 感染性腹泻, 硒酵母, 儿童

Abstract:
Objective
To explore the clinical effects of selenium yeast in the treatment of children with chronic infectious diarrhea.
Methods
We enrolled 56 children with infectious diarrhea in our hospital. They were randomly divided into observation group(n=28) and control group(n=28). In the control group, the 28 children received conventional treatment of conditioning diet, mucous membrane protection and reasonable fluid infusion. In the observation group, the 28 children received treatment of oral selenium yeast in addition to the conventional treatment. After the course of treatment of 14 days, we compared the clinical effects of the two groups, including frequency of bowel movement and the shape and property of feces.
Results
From the 6th day to the end of the treatment course, the rate of normal defecation in the observation group was higher than that of the control group(P<0.05). Similarly, the rate of normal feces in the observation group was higher than the control group(P<0.05).There was no adverse reactions related to selenium yeast.
Conclusion
Selenium yeast has good effect in the treatment of children with chronic infectious diarrhea, and there is no obvious adverse reaction, so it is worthy of clinical application.

Key words: Infectious diarrhea, Selenium yeast, Children