ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (1): 59-62.doi: 10.3969/j.issn.1674-3865.2019.01.016

• 临床研究 • 上一篇    下一篇

维生素A联合铁剂治疗学龄前儿童缺铁性贫血疗效观察

梁丽，郭先锋   

  1. 462000 河南 漯河，漯河市第二人民医院（漯河市儿童医院）小儿内科
  • 出版日期:2019-02-25 发布日期:2019-07-11
  • 通讯作者: 郭先锋，E-mail：guogu200020@163.com
  • 作者简介:梁丽（1986-），女，医学硕士，医师。研究方向：小儿呼吸、消化系统疾病的诊治

Effect of vitamin A combined with iron on iron-deficiency anemia in preschool children

LIANG Li，GUO Xianfeng   

  1. The Second People's Hospital Of Luohe，Luohe 462000，China
  • Online:2019-02-25 Published:2019-07-11

PDF (PC)

124

摘要：
目的
评价维生素A联合铁剂治疗学龄前儿童缺铁性贫血的临床疗效。
方法
选择2014年12月至2016年12月漯河市第二人民医院收治的缺铁性贫血患儿92例，随机分为观察组和对照组各46例。对照组患儿给予琥珀酸亚铁片，5 mg/（kg·d），分3次口服，连续服用30 d为1个疗程。观察组在对照组治疗基础上给予维生素A胶丸，每次2.5万U，每日1次，连服7 d，停药3 d后再服7 d，30 d内按此服用。比较两组临床疗效及治疗前后血红蛋白、血清铁蛋白含量、血清铁含量及总铁结合力。
结果
观察组临床总有效率为100.0%（46/46），显著高于对照组80.4%（37/46），差异有统计学意义（P<0.05）。观察组患儿经1个疗程治疗后血红蛋白、血清铁蛋白含量、血清铁含量及总铁结合力均高于对照组，差异有统计学意义（P<0.05）。
结论
维生素A联合铁剂治疗学龄前儿童缺铁性贫血效果显著，且疗效较单用铁剂治疗明显。

关键词: 缺铁性贫血, 维生素A, 琥珀酸亚铁, 学龄前儿童

Abstract:


Objective
To evaluate the clinical efficacy of vitamin A combined with iron in the treatment of iron-deficiency anemia in preschool children.
Methods
Ninety-two children were randomly divided into treatment group and control group, 46 cases in each group. The two groups were given ferrous succinate tablets orally, 5 mg/(kg·d), three times a day, for 30 consecutive days as a course of treatment. The treatment group was also given vitamin A capsules, 1 capsule/time, once a day, for 7 consecutive days, which was stopped for 3 days, and then resumed in the same pattern, within 30 days. The clinical efficacy, hemoglobin, serum ferritin, serum iron content and total iron binding capacity of the two groups were observed and compared before and after treatment.
Results
The hemoglobin, serum ferritin, serum iron content and total iron binding capacity in the treatment group were higher than those in the control group(P<0.05), and the curative effect was better than that in the control group(100.0% vs 80.4%)(P<0.05).
Conclusion
Vitamin A combined with iron is more effective than iron alone in the treatment of iron deficiency anemia in preschool children.

Key words: Iron-deficiency anemia, Vitamin A, Ferrous succinate, Preschool children