ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (2): 173-176.doi: 10.3969/j.issn.1674-3865.2019.02.023

• 临床研究 • 上一篇    下一篇

加味大柴胡汤治疗湿热型小儿急性阑尾炎的临床应用观察

张盟，秦晔   

  1. 110032 沈阳，辽宁中医药大学2016级临床中西医结合专业研究生（张盟）；辽宁中医药大学附属医院外科（秦晔）
  • 出版日期:2019-04-25 发布日期:2019-05-08
  • 通讯作者: 张盟，E-mail：94180882@qq.com
  • 作者简介:张盟（1993-）,男，辽宁中医药大学2016级硕士研究生在读。研究方向：外科疾病的中西医结合治疗

Clinical observation on modified Dachaihu decoction in the treatment of acute appendicitis of damp-heat type

ZHANG Meng，QIN Ye   

  1. Liaoning University of Traditional Chinese Medicine，Shenyang 110032,China
  • Online:2019-04-25 Published:2019-05-08

PDF (PC)

143

摘要：
目的
观察加味大柴胡汤联合西医常规治疗在湿热型急性阑尾炎的临床应用效果。
方法
选择2016年11月至2018年12月辽宁中医药大学附属医院收治的小儿急性阑尾炎患儿40例为研究对象，随机分为对照组20例和观察组20例。对照组嘱患儿禁食水，并给予常规补液治疗及抗感染治疗。观察组在对照组治疗基础上给予加味大柴胡汤进行治疗，10 d为1个疗程，观察两组患儿临床疗效及发热、腹痛和麦氏点压痛、反跳痛缓解时间；实验室指标（白细胞计数、C反应蛋白）。
结果
观察组总有效率为95.0%（19/20），显著高于对照组68.4%（13/20），差异有统计学意义（P<0.05）。两组患儿退热时间比较差异无统计学意义（P>0.05）。观察组患儿腹痛和压痛、反跳痛缓解时间低于对照组，差异有统计学意义（P<0.05）。在治疗第3、7天时观察组白细胞计数显著低于对照组，差异有统计学意义（P<0.05）；在治疗第7天时观察组C反应蛋白显著低于对照组，差异有统计学意义（P<0.05）。
结论
加味大柴胡汤联合西医基础治疗方案治疗湿热型小儿阑尾炎疗效显著。

关键词: 阑尾炎, 加味大柴胡汤, 中西医结合, 儿童

Abstract:
Objective
To observe the clinical effect of modified Dachaihu decoction combined with routine western medicine in the treatment of dampheat acute appendicitis.
Methods
The 40 children with acute appendicitis admitted to the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from November 2016 to December 2018 were randomly divided into control group (20 cases) and observation group(20 cases). The control group was told not to take any water, and routine rehydration treatment and antiinfection treatment were given. The observation group was treated with modified Dachaihu decoction on the basis of the treatment for the control group. The clinical efficacy, fever, abdominal pain, Maxwell's point tenderness and relief time of rebound pain, and laboratory indicators (white blood cell count, C-reactive protein) were observed.
Results
The total effective rate of the observation group was 95.0%(19/20), which was significantly higher than that of the control group(68.4%，13/20), and the difference was statistically significant(P<0.05). There was no significant difference in antipyretic time between the two groups(P>0.05). The relief time of abdominal pain, tenderness and rebound pain in the observation group was shorter than that in the control group, and the difference was statistically significant(P<0.05). The leucocyte count in the observation group was significantly lower than that in the control group on the 3rd and 7th day of treatment(P<0.05), and the Creactive protein in the observation group was significantly lower than that in the control group on the 7th day of treatment (P<0.05).
Conclusion
Modified Dachaihu decoction combined with basic treatment of Western medicine is effective in treating children with appendicitis of damp-heat type.

Key words: Appendicitis, Modified Dachaihu decoction, Integrated Traditional Chinese and Western Medicine, Children