ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (5): 381-395.doi: 10.3969/j.issn.1674-3865.2017.05.005

• 临床研究 • 上一篇    下一篇

白附饮配合中药注射针剂治疗小儿类百日咳综合征疗效观察

朱玲，喻闽凤，刘英，占科，朱卫娜，曾思瑶   

  1. 330006 南昌，江西中医药大学附属医院儿科
  • 出版日期:2017-10-25 发布日期:2017-12-18
  • 通讯作者: 喻闽凤，E-mail:ymf@163.com
  • 作者简介:朱玲（1988-），女，医学硕士，医师。研究方向：小儿推拿康复

Clinical observation of pediatric whooping cough syndrome treated by Baifuyin combined with traditional Chinese medicine injection

ZHU Ling，YU Minfeng，LIU Ying，ZHAN Ke，ZHU Weina，ZENG Siyao   

  1. Department of Pediatrics， Affiliated Hospital of Jiangxi University of TCM，Nanchang 330006，China
  • Online:2017-10-25 Published:2017-12-18

PDF (PC)

151

摘要：
目的
观察白附饮配合中药注射针剂治疗婴幼儿类百日咳综合征的临床疗效。
方法
选择2014年3月至2015年12月江西省中医院收治的类百日咳综合征痉咳期患儿60例为研究对象，随机分为观察组和对照组各30例。对照组给予环酯红霉素干混悬剂治疗，观察组给予白附饮联合喜炎平注射液和（或）喘可治注射液治疗。两组均治疗14 d。观察治疗前后主症和中医证候积分及临床疗效、不良反应情况。
结果
两组治疗7、14 d后主症及中医证候积分及总积分均显著低于治疗前，差异有统计学意义（P<0.01）。观察组治疗7、14 d后主症及中医证候积分及总积分均低于对照组，差异有统计学意义（P<0.05）。观察组治疗7、14 d后主症及中医证候有效率、临床总有效率均显著高于对照组，差异有统计学意义（P<0.05）。两组均未发生明显的不良反应。
结论
白附饮配合中药注射针剂的中医疗法治疗婴幼儿类百日咳综合征临床疗效可、安全性高、可行性好，值得在临床推广应用。

关键词: 类百日咳综合征, 痉咳期, 白附饮, 婴幼儿

Abstract:
Objective
To explore the clinical efficacy of Baifuyin combined with traditional Chinese medicine injection in the treatment of infants and young children with pertussis syndrome.
Methods
A total of 60 children with whooping cough syndrome were selected from March 2014 to December 2015. By random number table they were divided into observation group(30 cases) and control group(30 cases). The control group was treated with cyclamycin erythromycin dry suspension. The observation group was treated with Baifuyin combined with Xiyanping and/or Chuankezhi injection. Both groups were treated for 14 days. Observe the main symptoms and traditional Chinese medicine syndrome score before and after treatment as well as the clinical efficacy and adverse reactions.
Results
After treatment， the total scores,the scores of primary and TCM syndromes in the two groups were lower than those before treatment, and the difference was statistically significant(P<0.05). After 7d and 14d of treatment, the abovementioned scores were lower in observation group than in control group; the effective rate and total effective rate of TCM syndrome were significantly higher than those in the control group, and the difference was statistically significant(P<0.05).There was no obvious adverse reaction in the two groups.
Conclusion
The clinical curative effect of Baifuyin combined with traditional Chinese medicine injection is feasible and safe in the treatment of infants with whooping cough syndrome， which is worthy of clinical application.

Key words: Whooping cough syndrome, Stage of spasmodic cough, Baifuyin, Infants