ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2019, Vol. 11 ›› Issue (3): 272-274.doi: 10.3969/j.issn.1674-3865.2019.03.027

• 调查研究 • 上一篇    下一篇

鄂尔多斯地区儿童25羟维生素D水平调查与分析

萨日娜，王爱琼   

  1. 017000 内蒙古 鄂尔多斯，鄂尔多斯市中心医院儿科
  • 出版日期:2019-06-25 发布日期:2019-07-04
  • 通讯作者: 王爱琼，E-mail:Waq6588@163.com
  • 作者简介:萨日娜(1984-)，女，医学硕士，副主任医师。研究方向：儿童呼吸系统疾病、营养性疾病的诊治

Investigation and analysis of serum 25-hydroxy vitamin D level in children in Ordos area

SA Rina, WANG Aiqiong.   

  1. The Central Hospital of Ordos, Ordos 017000,China
  • Online:2019-06-25 Published:2019-07-04

PDF (PC)

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摘要： 目的
了解鄂尔多斯地区儿童维生素D营养状态，为临床合理补充维生素D提供依据。
方法
选取2016年8月至2018年8月鄂尔多斯市中心医院门诊体检的1 572例居住在鄂尔多斯地区的29 d至18岁健康儿童为研究对象，采用电化学发光法检测25-羟维生素D［25-(OH)D］水平。
结果
1 572例研究对象中维生素D缺乏779例(49.56%)，维生素D不足576例(36.64%)，维生素D充足217例(13.80%)。随年龄增长维生素D缺乏和不足更明显，9个月以前随着月龄增长维生素D水平增加，>9～12个月时达峰值，>1～18岁随着年龄的增长，维生素D水平不断下降。男孩与女孩25-(OH)D水平及维生素D缺乏率、不足率比较，差异均无统计学意义(P>0.05)。秋季血清25-(OH)D水平最高，冬季最低，二者比较差异有统计学意义(P<0.05)；其余各季节间比较差异无统计学意义(P>0.05)。
结论
鄂尔多斯地区的29 d至18岁健康儿童25-(OH)D水平较低，维生素D不足和缺乏普遍存在。

关键词: 维生素D缺乏, 维生素D不足, 25-羟维生素D, 儿童

Abstract: Objective
To investigate the nutritional status of vitamin D in children in Ordos area in order to provide basis for rational clinical supplementation of vitamin D.
Methods
Totally 1 572 healthy children aged 29 days to 18 years living in Ordos were included in this study, who took routine physical examination in our hospital from August 2016 to August 2018. Serum 25-hydroxy vitamin D(25-(OH)D) level was measured by electrochemiluminescence.
Results
Vitamin D deficiency existed in 779 cases(49.56%), vitamin D insufficiency in 576 cases(36.64%), and vitamin D sufficiency in 217 cases(13.80%) in the 1 572 subjects. Vitamin D deficiency and insufficiency were more obvious with the increase of age. Before 9 months of age, the vitamin D level increased with the increase of month age, and reached the peak between 9 and 12 months; and after 1 year of age the vitamin D level decreased continuously with the increase of age. There was no significant difference in 25-(OH)D level or vitamin D deficiency and insufficiency rate between boys and girls(P>0.05). The serum 25-(OH)D level was the highest in autumn and the lowest in winter(P<0.05), but there was no significant difference in other seasons(P>0.05).
Conclusion
The levels of 25-(OH)D in children aged 29 days to 18 years old in Ordos area are low, and vitamin D deficiency and insufficiency in children is common.

Key words: Vitamin D deficiency, Vitamin D insufficiency, 25-hydroxy vitamin D, Children