ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (5): 446-448.doi: 10.3969/j.issn.1674-3865.2017.05.027

• 调查研究 • 上一篇    下一篇

尿HBsAg检测在2 031名小学生健康年检中的意义

吕广秀，周娟，曹勇   

  1. 200052 上海，解放军八五医院儿科（吕广秀，周娟）|200333 上海，上海宏康医院儿科（曹勇）
  • 出版日期:2017-10-25 发布日期:2017-12-18
  • 通讯作者: 吕广秀，E-mail:lvguangxiu@sina.com
  • 作者简介:吕广秀（1962-），男，副主任医师。研究方向：儿科感染性疾病的诊治

Clinical value of urine HBsAg detection in the annual health examination of 2 031 children

LYU Guangxiu,ZHOU Juan,CAO Yong   

  1. Department of Pediatrics，the 85th Military Hospital，Shanghai 200052，China
  • Online:2017-10-25 Published:2017-12-18

PDF (PC)

150

摘要：
目的
探讨尿乙肝病毒表面抗原（HBsAg）检测的应用价值。
方法
选取2016年9月1日至10日上海市两所小学一至五年级全体小学生共2 031人为研究对象，其中市区小学980人和郊区小学1 051人。所有小学生均于开学第二周的周一留晨尿，应用ELISA方法检测尿中HBsAg，并对尿检阳性者予抽血复查乙肝相关指标。
结果
市区小学中980人，1人尿中HBsAg呈弱阳性，经专科医院复检后为阴性|郊区小学中1 051人，5人尿中HBsAg呈阳性，经专科医院血液检查，其中4人为HBsAg携带者，1人为大三阳（即HBsAg、HBeAg、HBcAb均阳性），5人肝功均正常。
结论
尿HBsAg检测可作为普通人群中及时发现HBsAg感染者的筛选方法之一，乙肝疫苗可较好保护机体，要按程序及时接种。

关键词: 乙肝病毒表面抗原, 尿, 儿童

Abstract:
Objective
To investigate the application value of HBsAg detection in urine.
Methods
A total of 2 031 pupils were included as the research subjects，980 of whom were from an urban elementary school and 1 051 from suburban school. Urine sanguinis was taken on Monday morning at the second week of a term. HBsAg in urine was detected by ELISA, and those with positive HBsAg testing were detected the hepatitis-B-related indexes.
Results
In the 980 from the urban school, one had slightly positive HBsAg, which was proved to be negative in the reexamination at a special hospital. In the 1 051 from the suburban school, 5 had positive HBsAg, and after the blood testing in a special hospital,4 were HBsAg carries, and one had positive HBsAg, HBeAg and HBcAb, and all the 5 pupils had normal liver function.
Conclusion
Urine HBsAg test can be a way of screening for people with HBsAg infection. Hepatitis B vaccine can protect our health, so we should receive vaccination in time as scheduled.

Key words: HBsAg, Urine, Children