ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (5): 448-450.doi: 10.3969/j.issn.1674-3865.2017.05.028

• 调查研究 • 上一篇    下一篇

小儿脑性瘫痪头MRI表现与中医证型的调查研究

高姗，关丽君   

  1. 110032 沈阳，沈阳市儿童医院康复二科
  • 出版日期:2017-10-25 发布日期:2017-12-18
  • 通讯作者: 关丽君，E-mail：13940599463@139.com
  • 作者简介:高姗（1984-），医学硕士，主治医师。研究方向：小儿脑性瘫痪的中西医结合治疗
  • 基金资助:
    辽宁省科学技术计划项目（2013225002）

Investigation of head MRI and TCM syndromes in children with cerebral palsy

GAO Shan，GUAN Lijun   

  1. Shenyang Children'S Hospital, Shenyang 110032,China
  • Online:2017-10-25 Published:2017-12-18

PDF (PC)

150

摘要：
目的
对小儿脑性瘫痪（简称脑瘫）头MRI表现与中医证型进行调查研究。
方法
选择2014年1月至2016年12月沈阳市儿童医院康复科收治住院的脑瘫患儿156例。中医辨证分型肝强脾弱证93例（59.62%），脾肾亏虚证22例（14.10%），痰瘀阻络证15例（9.62%），心脾两虚证26例（16.67%）。对患儿头部进行MRI检查，分析MRI表现与中医证型的关系。
结果
156例脑瘫患儿头MRI表现中，脑白质软化64例(41.02%)，脑外间隙增宽41例(26.28%)，侧脑室病变6例（3.84%），基底节病变19例(12.18%)，髓鞘形成不良16例(10.26%)，脑发育畸形3例(1.92%)，胼胝体病变7例(4.49%)。头MRI表现在各中医证型中，差异具有统计学意义(P<0.05)，脑白质软化与脑间隙增宽在肝强脾弱证中多于其他证型（P<0.05）。
结论
脑瘫患儿头MRI表现与中医证型存在一定内在联系。

关键词: 脑性瘫痪, 头MRI, 中医证型, 儿童

Abstract:
Objective
To study the head MRI manifestations and the TCM syndrome types in children with cerebral palsy.
Methods
A total of 156 children with cerebral palsy were selected, who were treated in Shenyang children's Hospital from Jan. 2014 to Dec. 2016.According to TCM syndrome differentiation, there were 93 cases of strong-liver and weak-spleen type(59.62%), 22 cases of spleen-kidney deficiency type(14.10%), 15 cases of phlegm and blood stasis type(9.62%),and heart-spleen weakness type(16.67%) . The head of these children was examined by MRI, and the relationship between MRI manifestations and TCM syndrome types was analyzed.
Results
In the 156 cases of cerebral palsy, there are 64 cases of leucomalacia(41.02%), 41 cases of extra-cerebral interval widening(26.28%), 6 cases of lateral ventricular lesion(3.84%),19 cases of basal ganglia lesion(12.18%), 16 cases of malformation of myelin sheath(10.26%), 3 cases of malformation of brain development(1.92%), and 7 cases of corpus callosum lesion(4.49%). The manifestations of head MRI had statistical difference in various TCM syndromes(P<0.05), and there were more cases of leucomalacia and cerebral interval widening in the strong-liver and weak-spleen syndrome than in other syndrome types(P<0.05).
Conclusion
There is an internal relationship between the MRI manifestations and TCM syndrome types in children with cerebral palsy.

Key words: Cerebral palsy, Head MRI, TCM syndrome type, Child