ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (1): 84-87.doi: 10.3969/j.issn.1674-3865.2017.01.026

• 调查研究 • 上一篇    下一篇

急性淋巴细胞白血病患儿化疗期疲乏症状调查

任伟，王建丽，李思静，张志红，吴玉梅，李瑞丹，常晓丹，石彩晓   

  1. 450000 郑州，郑州市儿童医院护理部(任伟，李思静，张志红，吴玉梅，李瑞丹，常晓丹，石彩晓),血液科(王建丽)
  • 出版日期:2017-02-25 发布日期:2017-12-18
  • 通讯作者: 石彩晓，E-mail：shicaixiao69@163.com
  • 作者简介:任伟(1969-)，女，医学硕士，主管护师。研究方向：小儿血液系统疾病的护理
  • 基金资助:
    国家自然科学基金项目(U1204806)

Investigation of the fatigue symptoms in children with ALL during chemotherapy

REN Wei，WANG Jianli，LI Sijing，ZHANG Zhihong，WU Yumei,LI Ruidan，CHANG Xiaodan，SHI Caixiao   

  1. Zhengzhou Children′s Hospital，Zhengzhou 450000，China
  • Online:2017-02-25 Published:2017-12-18

PDF (PC)

116

摘要： 目的:调查急性淋巴细胞白血病患儿化疗期疲乏症状状况。
方法:采用便利抽样法对2014年2月至2016年8月在郑州市儿童医院血液肿瘤科治疗的ALL化疗期患儿216例及其家长进行问卷调查。根据化疗不同治疗阶段分为3组，首次化疗组68例，非首次化疗组88例，化疗间歇期组60例。采用中文版PedsQL儿童多维疲乏量表对全身疲乏、休息疲乏、认知疲乏症状各维度进行评分。
结果:ALL患儿化疗期间疲乏症状总分为(33.19±23.17)分，其中全身疲乏维度平均得分为(11.94±7.59)分，睡眠疲乏维度平均得分为(11.80±7.70)分，认知疲乏维度平均得分为(9.45±7.88)分。患儿在化疗间歇期疲乏得分均高于首次化疗和非首次化疗，差异均有统计学意义(P<0.05)。
结论:急性淋巴细胞白血病患儿化疗期疲乏症状普遍存在，其中全身疲乏和睡眠疲乏症状处于中等水平，认知疲乏症状处于中等偏下水平；急性淋巴细胞白血病患儿化疗期不同治疗阶段疲乏症状存在差异，医务人员应该对不同疲乏症状进行评估并提供针对性症状管理。

关键词: 急性淋巴细胞白血病, 化疗期, 疲乏, 症状, 儿童

Abstract: Objective:To investigate the fatigue symptom of children with acute lymphoblastic leukemia(ALL)during chemotherapy.
Methods:Totally 216 children with ALL in Pediatric Hematology Departments of Children's Hospital in Zhengzhou City and their parents were investigated by questionnaire. According to chemotherapy stage, these children were divided into 3 groups: first therapy group(68 cases),non-first group(88 cases), and the interval group(60 cases), and they were surveyed by using Chinese version of Peds QLTM multidimensional fatigue scale.
Results:The total score of the fatigue symptom of children with ALL during chemotherapy was （33.19±23.17）.Average score of general fatigue was （11.94±7.59）.Average score of sleeping fatigue was（11.80±7.70）.Average score of cognitive fatigue was（9.45±7.88）.There was significant difference among different phases of chemotherapy（P＜0.05）.
Conclusion:Fatigue symptom is common in children with ALL, and score of general fatigue and sleeping fatigue is at average level, and the score of cognitive fatigue is below average level. Fatigue symptom of children with ALL are different during chemotherapy．Medical staff should evaluate symptoms of fatigue and provide targeted management of symptoms.

Key words: ALL, During chemotherapy, Fatigue, Symptom, Children