ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (4): 403-405.doi: 10.3969/j.issn.1674-3865.2016.04.010

• 临床研究 • 上一篇    下一篇

润肺止咳汤在小儿咳嗽变异性哮喘治疗中的应用价值分析

丁东婧   

  1. 400014 重庆，重庆医科大学附属儿童医院中医科
  • 出版日期:2016-08-25 发布日期:2018-11-19
  • 作者简介:丁东婧(1979-)，女，医学硕士，主治医师。研究方向：中医儿科的研究，E-mail：luckyddj@163.com

Application value analysis of Runfei Zhike decoction in the treatment of infantile cough variant asthma

DING Dongjing   

  1. Children's Hospital of Chongqing Medical University,Chongqing 400014，China.
  • Online:2016-08-25 Published:2018-11-19

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摘要：
目的：分析润肺止咳汤治疗小儿咳嗽变异性哮喘(CVA)的临床价值。
方法：2013年4月至2015年12月重庆医科大学附属儿童医院中医科收治住院的CVA患儿106例，随机分为对照组和观察组各53例。对照组给予孟鲁司特钠与氯雷他定口服，观察组以自拟润肺止咳汤进行治疗，两组患儿均连续治疗7 d。观察两组临床疗效、治疗前后症状积分及白细胞介素2、白细胞介素6浓度，治疗期间有无不良反应。
结果：观察组治疗总有效率为96.2%(51/53)，显著高于对照组75.5%(40/53)，差异有统计学意义(P<0.01)；治疗后两组临床症状总积分、血清白细胞介素2、白细胞介素6水平均低于治疗前，差异有统计学意义(P<0.05)；治疗后观察组临床症状总积分、血清白细胞介素2、白细胞介素6水平均低于对照组，差异有统计学意义(P<0.05)。
结论：润肺止咳汤治疗小儿咳嗽变异性哮喘疗效显著，临床症状改善显著，值得临床推广。

关键词: 咳嗽变异性哮喘, 润肺止咳汤, 临床症状, 儿童

Abstract:


Objective：To analyze clinical value of Runfei Zhike decoction in the treatment of infantile cough variant asthma.
Methods：Totally 106 cases of cough variant asthma(CVA) who was admitted to the Children's Hospital of Chongqing Medical University from April 2013 to December 2015 have been selected in this study and were randomly divided into control group and observation group, each group with 53 cases. The control group was treated with montelukast sodium and oral loratadine, and the observation group was treated with self-made Runfei Zhike decoction; the patients of the two groups were treated continuously for 7 days. Observe the clinical efficacy of the two groups, the symptom score, interleukin IL-2 and leukocyte interleukin 6 levels before and after treatment; observe the adverse reactions during the treatment.
Results：The total effective rate of the observation group was 96.2%(51/53), which was significantly higher than that of the control group(75.5%,40/53),and the difference was statistical(P<0.01).The clinical symptoms score and the levels of interleukin 2 and 6 were all lower after treatment than before, and there was statistical difference(P<0.05).
Conclusion：Runfei Zhike decoction is very effective in the treatment of children with cough variant asthma, with the clinical symptoms significantly improved, so it is worth popularization in clinics.

Key words: Cough variant asthma, Runfei Zhike decoction, Clinical symptoms, Child