ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (4): 406-408.doi: 10.3969/j.issn.1674-3865.2016.04.011

• 临床研究 • 上一篇    下一篇

1型糖尿病患儿血清维生素A和维生素D水平及其临床意义

牛文忠，丁显春   

  1. 473000 河南 南阳，南阳市中心医院儿科
  • 出版日期:2016-08-25 发布日期:2018-11-19
  • 通讯作者: 丁显春，E-mail：erkedxc@126.com
  • 作者简介:牛文忠(1978-)，男，医学硕士，主治医师。研究方向：小儿内分泌疾病的诊治

Clinical significance of serum level of vitamin A and vitamin D in children with type 1 diabetes mellitus

NIU Wenzhong，DING Xianchun   

  1. Department of Pediatrics，Nanyang Central Hospital, Nanyang 473000，China.
  • Online:2016-08-25 Published:2018-11-19

PDF (PC)

98

摘要：
目的：分析1型糖尿病(T1DM)患儿血清维生素A和维生素D水平变化及其临床意义。
方法：2012年2月至2015年1月南阳市中心医院儿科收治住院的T1DM患儿45例，为T1DM组，其中27例合并酮症酸中毒(DKA)。同期选取本院健康体检儿童38例，为对照组。采用酶联免疫吸附法测定血清维生素A和维生素D水平。
结果：T1DM患儿血清维生素A和维生素D水平均低于对照组，差异有统计学意义(P<0.05)。单纯T1DM患儿血清维生素A和维生素D与T1DM合并DKA患儿比较差异均无统计学意义(P>0.05)。
结论：及时、足量补充维生素A和维生素D可能降低或延迟儿童T1DM发病

关键词: 1型糖尿病, 维生素A, 维生素D, 儿童

Abstract:
Objective：To analyze the level of serum vitamin A and vitamin D in children with T1DM and its clinical significance.
Methods：From February 2012 to January 2015 in Pediatrics Department of Nanyang Central Hospital,45 children with T1DM were selected as T1DM group,27 cases with DKA| 38 healthy children undergoing physical examination at the same time period were selected as control group. The level of vitamin A and vitamin D were detected by ELISA.
Results：The level of serum vitamin A and vitamin D in T1DM group was lower than that in control group(P<0.05). The level of serum vitamin A and vitamin D had no significant differences in children with simple T1DM and children combined with DKA(P>0.05).
Conclusion：Timely and adequate supplement of vitamin A and vitamin D may reduce or delay the onset of T1DM in children.

Key words: T1DM, Vitamin A, Vitamin D, Children