ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2015, Vol. 7 ›› Issue (5): 433-436.doi: 10.3969/j.issn.1674-3865.2015.05.008

• 临床研究 • 上一篇    下一篇

口服匹多莫德联合咳喘灵口服液治疗螨过敏性哮喘患儿长期疗效分析

张向峰   

  1. 450000 郑州,郑州市儿童医院呼吸内科
  • 出版日期:2015-10-25 发布日期:2015-11-19
  • 作者简介:张向峰(1979-),男,主治医师。研究方向:小儿呼吸内科相关疾病的诊治。

Long-term effect of oral pidotimod combined with Kechuanling oral liquid in the treatment of mite allergic asthma

ZHANG Xiangfeng   

  1. Department of Internal Medicine, Zhengzhou Children's Hospital, Zhengzhou 450000, China
  • Online:2015-10-25 Published:2015-11-19

摘要:
目的
:观察口服匹多莫德联合咳喘灵口服液治疗螨过敏性哮喘患儿的长期疗效。
方法:对86例螨过敏性哮喘患儿的临床资料进行分析。采用口服匹多莫德联合咳喘灵口服液治疗44例(联合组),单纯采用匹多莫德治疗42例(单药组),均随访3年,比较两组患儿治疗第2年和第3年结束时的哮喘日间和夜间症状评分、治疗第3年期间哮喘急性发作频率。
结果:联合组患儿治疗第2年结束时和第3年结束时的哮喘症状评分明显低于单药组,差异有统计学意义(P<0.05)。治疗第3年期间联合组患儿急性发作频率为27.27%(12/44),低于单药组57.14%(24/42),差异有统计学意义(P<0.05)。
结论:口服匹多莫德联合咳喘灵口服液治疗螨过敏性哮喘可明显改善患儿的哮喘症状,降低哮喘急性发作频率,长期疗效良好,具有临床推广价值。

关键词: 哮喘,过敏性, 匹多莫德/治疗应用, 咳喘灵口服液/治疗应用, 儿童

Abstract:
Objective:
To observe the long-term efficacy of oral pidotimod combined with Kechuanling oral liquid in the treatment of children with mite allergic asthma.
Methods:The clinical data of 86 cases of allergic asthma were analyzed,and they were divided into two groups:the pidotimod combined with Kechuanling oral liquid in the treatment of 44 cases (combination group),simple pidotimod treatment of 42 cases (single group);they were followed up for 3 years. Compare the day and night symptom scores at the end of 2nd and 3rd year of treatment as well as the asthma exacerbation frequency during the 3rd year of treatment.
Results:At the end of the second year and the end of the third year, the asthma symptoms score in the combination group was significantly lower than that of the single group, the difference being statistically significant(P<0.05). The frequency of acute attack of the combination group was 27.27%(12/44), lower than that of the single group(57.14%,24/42), and the difference was statistically significant(P<0.05).
Conclusion:Pidotimod combined with Kechuanling oral liquid in the treatment of mites allergic asthma can significantly relieve the symptoms of asthma in children and reduce asthmatic exacerbation frequency, with good long-term results and great clinical value.

Key words: asthma/allergic, pidotimod/treatment application, Kechuanling oral liquid/treatment application, children

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