Abstract:
Objective
To investigate the effect of Qingfei Pingchuan decoction on tidal breathing lung function in infants with respiratory syncytial virus pneumonia(phlegm-heat closing lung).
Methods
A total of 140 children with respiratory syncytial virus pneumonia(phlegm-heat closing lung) were randomly divided into two groups, 70 in the observation group and 70 in the control group. Because some children were eliminated during treatment due to the inclusion criteria and some were lost, finally the observation group consisted of 68 cases and the control group,66 cases. Both groups were given symptomatic treatment including antivirus treatment and inhalation, and antibiotics were used for those with bacterial infection. In addition, the observation group was treated with self-made Qingfei Pingchuan decoction for treatment. The treatment lasted for 7 to 14 days. The relief time of signs and symptoms, the absoption time of chest X-ray and the length of hospital stay were observed, and the changes in the tidal breathing lung function before and after treatment were also observed in the two groups.
Results
The total effective rate of observation group was 95.6%(65/68),significantly higher than that of control group (81.8%,54/66),there being statistical different(P＜0.05).The time for fever, cough, asthma and lung rales to disappear, the absorption time of chest X-ray and the length of hospital stay were all shorter in the observation group than those in the control group after treatment, and there was statistical difference(P＜0.05).Comparing the tidal breathing lung function of the two groups before and after treatment, there was statistical different in the detection of TI/TE, Vt/kg, RR, TPEF／TE,VPEF/VE, TEF 25％,TEF 50％ and TEF 75％(P＜0.05).Comparing the Vt/kg, VPEF/VE and TPEF／TE between the two groups after treatment, there was statistical difference(P＜0.05).
ConclusionThe tidal breathing lung function is obviously damaged in children with respiratory syncytial virus pneumonia(phlegm-heat closing lung).After the clinical symptoms are relieved, the lung function is improved significantly, and the improvement in Vt/kg, TPEF／TE and VPEF/VE is greater in observation group than in control group. Qingfei Pingchuan decoction has significant effect in improving the lung function of children with respiratory syncytial virus pneumonia.

Key words: Respiratory syncytial virus pneumonia, Phlegm-heat closing lung, Qingfei Pingchuan decoction, Tidal breathing lung function, Child