Objective
To observe the Effect of Qingxin Xiepi method on myocardial enzymes and leucocyte classification in children with hand-foot-mouth disease(heart-spleen-Methods
Thirty children with hand, foot and mouth disease admitted to Guangzhou Hospital of TCM from May 2016 to November 2017 were selected as the observation group. At the same time, 60 healthy children were selected as the control group. Myocardial enzymes and leucocytes were detected before and after treatment in the observation group and in the control group.

Results
(1)LDH,α-HBDH, white blood cell count, neutrophil absolute value, neutrophil percentage, neutrophil to lymphocyte ratio(N/L) and monocyte absolute value in the observation group before treatment were higher than those in the control group, while CK, CK-MB and lymphocyte percentage were lower(P<0.05).(2) After treatment, the levels of LDH, αHBDH, white blood cell count, absolute value of neutrophils, percentage of neutrophils, ratio of neutrophils to lymphocytes(N/L), absolute value of monocytes and percentage of monocytes in the observation group were significantly lower than those before treatment, while the absolute value of lymphocytes and percentage of lymphocytes were significantly higher(P<0.05).(3) The clinical symptoms of fever, oral herpes and hand-foot herpes in the observation group were significantly improved after treatment compared with those before treatment(P<0.05).

Conclusion
Myocardial enzymes and leukocyte classification are improved significantly by using the Qingxin Xiepi method in children with hand-foot-mouth disease(heart-spleen-heat type). It provides a theoretical basis for the efficacy of the prescription.