ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2019, Vol. 11 ›› Issue (4): 322-326.doi: 10.3969/j.issn.1674-3865.2019.04.013

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Rule of using traditional Chinese medicine gel in the treatment of epilepsy in children based on traditional Chinese medicine inheritance assistant system

JIAO Yang,CHE Wenjin,ZHANG Baoqing   

  1. First Clinical College of Shandong University of Traditional Chinese Medicine, Jinan 250014,China
  • Online:2019-08-25 Published:2019-09-18

Abstract:
Objective
To analyze and summarize the experience and rule of using traditional Chinese medicine gel in the treatment of epilepsy in children by using traditional Chinese medicine inheritance assistant system, so as to provide reference for clinical treatment of epilepsy in children with the gel.
Methods
Collect the cases of pediatric epilepsy treated by Prof. Zhang Baoqing with medicinal gel in the Pediatric Outpatient Department of Affiliated Hospital of Shandong University of Traditional Chinese Medicine; input the information of the prescription into the "Traditional Chinese Medicine Inheritance Assistant System". The data mining methods were adopted, such as improved mutual information method, complex system entropy aggregation method and unsupervised entropy hierarchical clustering method, and the rule of the gel prescriptions in the treatment of pediatric epilepsy was analyzed.
Results
Statistical analysis was conducted in 115 selected gel prescriptions, including 112 kinds of traditional Chinese medicines. The number of times and frequency of drug use in prescriptions were obtained. Fourteen core combinations and seven potential new combinations were discovered through analyzing the association among drugs.
Conclusion
Nowadays, most of the gel prescriptions for treating epilepsy in children include medicines tonifying deficiency, resolving phlegm, regulating qi and calming liver. The treatment is based on tonifying kidney and calming liver, supplemented by invigorating spleen. The methods of eliminating phlegm and resuscitating Qi, invigorating kidney and tranquilizing liver and calming wind are adopted.

Key words: Epilepsy, Traditional Chinese medicine gel, Traditional Chinese medicine inheritance assistant platform, Prescription medication rule, Child