ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2020, Vol. 12 ›› Issue (5): 442-446.doi: 10.3969/j.issn.1674-3865.2020.05.021

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Study on medication laws of Chinese medicine in the treatment of allergic rhinitis in infants based on cluster analysis and association rules

  

  • Online:2020-10-25 Published:2020-11-28

Abstract: Objective To study the medication laws of Chinese medicine in the treatment of allergic rhinitis in infants in the past 20 years. Methods The clinical research literatures on Chinese medicine treatment for allergic rhinitis in infants were collected from China Academic Journal Fulltext Database, Chinese Science and Technology Journal Database and Wanfang Data Knowledge Service Platform. The data were extracted from the literatures that meet the screening criteria. Descriptive statistics was made on the frequency of drug use, and the effect, classification, nature and taste of the drugs and the meridians affected, and then cluster analysis and association analysis were performed. Results The most commonly used drugs in the treatment of infants with allergic rhinitis were exteriorreleasing drugs and tonic medicines, mainly those dispersing windcold and tonifying Qi. The medicines most commonly used were warm in nature and pungent, sweet and bitter in taste, and the meridians that were affected were those of lungs, spleen, stomach, liver and heart. Four cluster prescription were formulated and they were C1(Atractylodes macrocephala, Astragalus, Fangfeng),C2(Xanthium sibiricum, Radix Angelicae dahuricae, Xinyi, Chuanxiong, Asarum),C3(Wumei, Schisandra, Guizhi, ephedra),C4(Poria, Codonopsis,Licorice). Conclusion The summary of the medication laws in the treatment of infants with allergic rhinitis shows that in clinical treatment Yupingfeng powder combined with Xanthium powder(modified) is commonly used, and differentiation medication is performed based on the relevant clinical symptoms.

Key words: Allergic rhinitis, Traditional Chinese medicine, Cluster analysis, Association rules, Medication laws, Children