ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2015, Vol. 7 ›› Issue (5): 442-445.doi: 10.3969/j.issn.1674-3865.2015.05.012

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Observation on the effect of combination treatment with traditional Chinese medicine and ganciclovir for human cytomegalovirus pneumonia in children

ZHAO Jianling,TAO Fenggui,ZHOU Huiping   

  1. Imaging Department,Liangzhou Hospital,Wuwei 733000,China
  • Online:2015-10-25 Published:2015-11-19

Abstract:
Objective:
To observe the clinical effect of the combination treatment with traditional Chinese medicine and ganciclovir for cytomegalovirus pneumonia in children.
Methods:A total of 95 cases of cytomegalovirus pneumonia were randomly divided into two groups:the observation group(48 cases) and the control group(47 cases).The control group was given intravenous drip as symptomatic treatment with ganciclovir(5 mg/kg) and 5% glucose(1∶1),twice a day for 14 days to reduce sputum and relieve cough.In the observation group,traditional Chinese medicine was used in addition to the above treatment.Observe the changes of the symptoms and signs of the children after 14 days.
Results:The serum ALT,AST,AKP,GT,TBIL and DB in the observation group decreased more significantly than the control group after treatment,the difference being of statistical difference(P<0.05);the cure rate of the observation group was 91.7%(44/48),significantly higher than the control group(61.7%,29/47),with statistical difference(P<0.05).
Conclusion: Traditional Chinese medicine combined with ganciclovir has good therapeutic effect on cytomegalovirus pneumonia,with no liver dysfunction,which should be clinically recommended.

Key words: pneumonia, cytomegalovirus infection, ganciclovir/treatment application, children

CLC Number: