Abstract:
Objective：To observe the clinical effect and safety of clonazepam for intramuscular injection and enema in the treatment of infantile convulsion.
Methods：Ninety children with convulsion were randomly divided into 3 groups：group of clonazepam for intramuscular injection(A)，group of clonazepam for enema (B) and control group(C)，with 30 cases in each.Group A was given clonazepam at 0.05 mg/kg for intramuscular injection；group B was given clonazepam at 0.1 mg/kg for enema；control group was given luminal at 5 mg/kg for intramuscular injection.Observe the treatment results and adverse reactions.
Results： Total effective rate was 90.0%(27/30) in both group A and group B，which was 63.3%(19/30) in group C，the difference being of statistical significance(P＜0.017).There was no significant difference between group A and group B(P＞0.017).There was no relapse in either group A or B，while there were 8 cases of relapse in group C.There was no respiratory depression or circulation disorder in all the 3 groups after treatment.
Conclusion：Clonazepam for intramuscular injection and enema is effective in the treatment of infantile convulsion.It is safe and easy to perform with no adverse reaction，which is worthy of being applied in the local hospitals.

Key words: convulsion, clonazepam/treatment application, luminal/treatment application, intramuscular injection, enema, children