ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2015, Vol. 7 ›› Issue (5): 450-453.doi: 10.3969/j.issn.1674-3865.2015.05.015

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Effect observation of large-dose vitamin C in treating acute glomerulonephritis in children

WANG Yong, FANG Hongxing, SUN Yajun, LIU Huimin   

  1. Children's Hospital of Kaifeng City,Kaifeng 475000,China
  • Online:2015-10-25 Published:2015-11-19

Abstract:
Objective:
To investigate the clinical effect of large-dose vitamin C in treating acute glomerulonephritis.
Methods:Eighty cases of acute glomerulonephritis were divided into control group and observation group, 40 cases in each group. The control group was given conventional western medicine and observation group was given large-dose vitamin C in addition to the conventional western medicine. After 4 weeks of treatment, observe the extinction of edema,blood sedimentation, routine urine test and complement change of the two groups.
Results:Total effective rate of the two groups had no statistical significance(P>0.05). Cure rate of observation group was 70.0%(28/40), higher than control group(47.5%,19/40), the difference being statistically significant(P<0.05). Extinction of edema, blood sedimentation, routine urine test and complement of observation group had shorter recovery time than control group, the difference being statistically significant(P<0.05).
Conclusion:Large-dose vitamin C plays an important role in the treatment of acute glomerulonephritis. It is worthy of wide application.

Key words: glomerulonephritis/treatment, vitamin C/treatment application, children

CLC Number: