Abstract:
Objective：To sum up the clinical characteristics of infectious mononucleosis in children in order to get early diagnosis and treatment.
Methods：A retrospective analysis of 55 cases of infectious mononycleosis by EBV infection in our hospital was carried out.
Results：The clinical manifestations of the disease mainly were: fever 98.2% (54/55),angina 100% (55/55),lymph node enlargement 87.2% (48/55),liver enlargement 32.7% (18/55),splenomegaly 49.1% (27/55),eyelid edema 54.5% (30/55),nasal obstruction 29.0% (16/55),and rash 23.6% (13/55). Laboratory examination: peripheral blood white blood cell count was greater than 10×10⁹/L in 96% (53/55); EBV-DNA was positive in all cases, with liver function damage, myocardial damage, or pneumonia. Ganciclovir treatment was effective.
Conclusion：The clinical manifestations of infectious mononucleosis are complex and diverse, which can be complicated with multiple organ damage, but most of the prognosis is good. EBV-DNA detection has specificity, which can improve the early diagnosis of the disease. Ganciclovir treatment is effective.

Key words: infectious mononucleosis/therapy, ganciclovir/therapeutic use, children