Abstract:
Objective：To observe the preventive effect of Saccharomyces boulardii on secondary diarrhea after surgical reduction for intussusception.
Methods：The children receiving only emergency operative reduction for intussusception were randomly divided into the observation group (given boulardii) (94 cases)and the control group (no boulardii) (88 cases) after operation.. All of the patients were checked the stool occult blood and rotavirus antigen, and received other preoperative examinations. After operation conditions of the stool were paid attention to,and if diarrhea stool occult blood occurred,we immediately reexamined rotavirus antigen.
Results：In the observation group and the control group the incidence of secondary diarrhea was 6.3% (6/94)and 12.5% (11/88)respectively, the difference between the two groups having statistical significance (χ²=4.63,P=0.03); postoperative time of diarrhea was (3.24±1.22) d and (4.63±1.14)d, the difference between the two groups having statistical significance (F=5.14, P=0.022). All patients were cured and discharged. There was no recurrence of intussusception, wound infection, dehiscence, allergies or other conditions, and the discharge stools were normal.
Conclusion：Saccharomyces boulardii, in terms of the prevention of secondary diarrhea after surgical reduction for intussusception can be applied to treatment.

Key words: diarrhea, Saccharomyces boulardii/treatment application, intussusception/operation, reduction, children