ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (1): 1-3.doi: 10.3969/j.issn.1674-3865.2016.01.001

• 临床论著 •    下一篇

平喘方治疗小儿热性哮喘的临床研究

李美花，薛征，阮艳艳，姜永红，陈伟斌   

  1. 030024 太原，山西中医学院研究生部(李美花)；200071 上海，上海中医药大学附属市中医医院儿科(薛征)；100000 北京，北京市通州区中西医结合医院儿科(阮艳艳)；200032 上海，上海中医药大学附属龙华医院儿科(姜永红)；200437 上海，上海中医药大学附属岳阳医院儿科(陈伟斌)
  • 出版日期:2016-02-25 发布日期:2018-11-19
  • 通讯作者: 薛征，E-mail：xz695@163.com
  • 作者简介:李美花(1987-)，女，山西中医学院2013级硕士研究生在读。研究方向：中医儿科呼吸系统疾病的诊治
  • 基金资助:
    上海市卫生和计划生育委员会中医药科研基金课题(2014LP077A)

Clinical study on asthmarelieving prescription for children with thermal asthma 

LI Meihua，XUE Zheng，RUAN Yanyan，JIANG Yonghong，CHEN Weibin   

  1. Graduate School of Shanxi TCM College，Taiyuan 030024，China
  • Online:2016-02-25 Published:2018-11-19

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摘要：
目的：采用多中心研究方法观察平喘方治疗儿童热性哮喘的临床疗效。
方法：2014年8月至2015年6月上海市中医药大学3家附属医院(上海市中医医院、龙华医院、岳阳医院)儿科收治哮喘发作期辨证属于热性哮喘的患儿180例，随机分为对照组和观察组各90例。观察组用平喘方治疗，对照组用麻杏石甘汤治疗，疗程均为7 d。观察并比较两组治疗前后主要症状体征积分变化及临床疗效。
结果：两组治疗后的主要症状体征(气喘、咳嗽、胸闷、哮鸣音)积分与治疗前比较均减小，差异有统计学意义(P＜0.05)。治疗后观察组气喘、咳嗽、胸闷、哮鸣音症状积分均小于对照组，差异有统计学意义(P＜0.05)。观察组总有效率为96.7%(87/90)，显著高于对照组83.3%(75/90)，差异有统计学意义(P＜0.05)。
结论：平喘方对小儿哮喘发作期热性哮喘疗效显著，且优于麻杏石甘汤。

关键词: 哮喘, 哮喘持续状态, 平喘方, 治疗效果, 儿童

Abstract:
Objective：To observe the clinical effect of asthma-relieving prescription for children with thermal asthma by multi-center research method.
Methods：A total of 180 children were included in the study，who were admitted to the Pediatric Department of the 3 affiliated hospital of Shanghai TCM University from August 2014 to June 2015 for thermal asthma at acute stage.They were divided into two groups:the control group and the observation group，with 90 cases in each group.The observation group was treated with asthma-relieving prescription，and the control group was given Maxing Shigan decoction for treatment.The treatment lasted for 7 days，and compare the score change of main symptoms and signs as well as the clinical effect before and after treatment between the two groups.
Results：The score of main symptoms and signs in two groups(wheezing，cough，chest tightness，wheezing rale) were decreased after treatment，the difference being statistically significant(P＜0.05)，and these scores in the observation group were smaller than those of the control group after treatment，the difference being of statistical significance(P＜0.05).The total effective rate was 96.7%(87/90) in the observation group，significantly higher than that of the control group［83.3%(75/90)］，and the difference was statistically significant(P＜0.05).
Conclusion：The asthma-relieving prescription has good effect in the treatment of children with thermal asthma at acute stage，and it's better than Maxing Shigan decoction.

Key words: Asthma, Asthma at acute stage, Asthma-relieving prescription, Curative effect, Child