ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (4): 307-310.doi: 10.3969/j.issn.1674-3865.2018.04.010

• 临床研究 • 上一篇    下一篇

穴位贴敷治疗小儿厌食症的疗效及对食欲调节因子的影响

王利然   

  1. 450000 郑州，郑州市中医院汝河路院区儿科
  • 出版日期:2018-08-25 发布日期:2018-12-03
  • 通讯作者: 王利然，E-mail:22529083@qq.com
  • 作者简介:王利然（1980-），女，医学硕士，主治医师。研究方向：儿童常见疾病中西医结合治疗
  • 基金资助:
    郑州市科技局2012年普通科技攻关计划项目(20120906)

Clinical observation on acupoint application in the treatment of anorexia in children and its effect on appetite regulation factor

WANG Liran   

  1.  Department of Pediatrics, Zhengzhou Hospital of Traditional Chinese Medicine，Zhengzhou 450000, China
  • Online:2018-08-25 Published:2018-12-03

PDF (PC)

130

摘要：
目的
探讨自制膏药穴位贴敷治疗小儿厌食症的疗效及对食欲调节因子的影响。
方法
选择2017年1月至8月在郑州市中医院儿科收治的厌食症患儿80例为研究对象，随机分为观察组和对照组各40例。两组患儿均给予纠正不良饮食习惯以及饮食调整等基础治疗。对照组口服双歧杆菌，每次1.0 g，每日3次。2周为1个疗程，共4个疗程。观察组在对照组治疗基础上给予自制膏药穴位贴敷。膏药每周前3天每天贴敷1次，后4天暂停，2周为1个疗程，共4个疗程。观察两组临床治疗效果、治疗前后中医证候积分；治疗前后血清瘦素以及神经肽Y水平；停药6个月及1年后随访观察复发率。
结果
观察组完成39例，失联1例；对照组完成38例，因胶布过敏退出治疗1例，厌食因继发性疾病引起1例退出研究。观察组总有效率为94.9%（37/39），显著高于对照组76.3%（29/38），差异有统计学意义（P<0.05）。两组治疗后中医证候积分均低于治疗前，差异有统计学意义（P<0.05）。观察组治疗后中医证候积分低于对照组，差异有统计学意义（P<0.05）。两组治疗后血清瘦素及神经肽Y水平均高于治疗前，差异有统计学意义（P<0.05）；观察组治疗后血清瘦素及神经肽Y水平均高于对照组，差异有统计学意义（P<0.05）。观察组患儿治疗后随访6个月和1年复发率均低于对照组，差异有统计学意义（P<0.05）。
结论
膏药穴位贴敷联合双歧杆菌治疗儿童厌食症疗效佳，能显著改善患儿营养状况，且复发率低，其作用与升高血清瘦素及神经肽Y水平有关。

关键词: 厌食症, 穴位贴敷, 儿童

Abstract:
Objective:
To discuss the effect of acupoint application of self-made plaster on anorexia in children and its effect on appetite regulation factor.
Methods:
Eighty children with anorexia were divided into the observation group(n=40) and control group(n=40) at random, Both groups of children were given basic treatment, such as correcting bad eating habits and dietary adjustment. Both groups took bifidobacterium orally, 1.0 g at a time, 3 times a day. The observation group also received acupoint application of self-made plaster, once a day for the first three days in a week, and was suspended for the next four days. The treatment lasted for 4 courses, with 2 weeks in a course. Observe clinical results，TCM syndrome score, serum leptin and neuropeptide Y levels before and after clinical treatment in the two groups. The recurrence rate was observed after 6 months and 1 year of discontinuation was also observed.
Results:
In the observation group 39 cases completed the treatment and one case lose. In the control group 38 cases completed the treatment, including 1 patient who had withdrawn from treatment due to adhesive allergy, and 1 patient who had anorexia due to secondary diseases. The total clinical effective rate in observation group(94.9%,37/39) was much higher than that in control group(76.3%,29/38)(P<0.05),the difference being statistical. The TCM syndrome score of both groups was lower than that before treatment, and the difference was statistically significant (P<0.05).Serum leptin and neuropeptide Y levels were higher in both groups after treatment than before treatment, and the difference was statistically significant(P<0.05).Serum leptin and neuropeptide Y levels in the observation group were higher than those in the control group after treatment, and the difference was statistically significant (P<0.05).The recurrence rate of children in the observation group was lower than that of the control group at 6 months and 1 year followup after treatment, and the difference was statistically significant(P<0.05).
Conclusion:
Acupoint application of plaster combined with bifidobacterium in the treatment of anorexia in children has a good effect, which can significantly improve the nutritional status of children, and the recurrence rate is low, and its effect is related to the increase of serum leptin and neuropeptide Y levels.

Key words: Anorexia, Acupoint application, Children