ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (1): 72-74.doi: 10.3969/j.issn.1674-3865.2020.01.020

• 临床研究 • 上一篇    下一篇

特布他林治疗对支原体肺炎患儿肺功能及炎症因子的影响

陈银   

  1. 463200 河南 驻马店,河南省确山县人民医院儿科
  • 出版日期:2020-02-25 发布日期:2021-05-17
  • 作者简介:陈银(1982-),女,主治医师。研究方向:儿科常见疾病的诊治,E-mail:fuermai35647@163.com

Effects of terbutaline on pulmonary function and inflammatory factors in children with mycoplasma pneumonia

  • Online:2020-02-25 Published:2021-05-17

摘要: 目的 探讨特布他林治疗对支原体肺炎患儿肺功能及炎症因子的影响。 方法 选取2018年1月至2019年3月本院收治的支原体肺炎患儿80例,随机分为对照组和观察组各40例。对照组给予阿奇霉素序贯治疗,观察组在此基础上给予特布他林治疗。对比两组肺功能及炎症因子水平。 结果 治疗后观察组第一秒用力呼气量(FEV1)、最大呼吸峰流速(PEF)以及第一秒用力呼气容积占用力肺活量的百分比(FEV1/FVC)均高于对照组,嗜酸性粒细胞(EOS)、白细胞介素2(IL-2)、白细胞介素4(IL-4)均低于对照组,差异有统计学意义(P<0.05)。 结论 给予支原体肺炎的患儿采用特布他林治疗效果确切,可改善肺功能,降低炎症因子水平。

关键词: 支原体肺炎, 特布他林, 阿奇霉素, 肺功能, 炎症因子

Abstract: Objective To investigate the effect of terbutaline on pulmonary function and inflammatory factors in children with mycoplasma pneumonia. Methods Eighty children with mycoplasma pneumonia were selected from our hospital who were treated from January 2018 to March 2019.They were randomly divided into control group and experimental group,40 cases each.The control group was given azithromycin sequential treatment,and on this basis,the patients of experimental group were given terbutaline treatment.The lung function and inflammatory factors were compared between the two groups. Results FEV1,PEF and FEV1/FVC of the experimental group were higher than those of the control group,while eosinophils,IL-2 and IL-4 were lower than those of the control group(P<0.05). Conclusion the therapeutic effect of terbutaline on children with mycoplasma pneumonia is definite,which can improve lung function and reduce the level of inflammatory factors.

Key words: Mycoplasma pneumonia, Terbutaline, Azithromycin, Pulmonary function, Inflammatory factors