ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (1): 67-69.doi: 10.3969/j.issn.1674-3865.2017.01.021

• 临床研究 • 上一篇    下一篇

小儿豉翘颗粒联合利巴韦林气雾剂治疗手足口病疗效观察

于四景   

  1. 410007 长沙，湖南省儿童医院感染科
  • 出版日期:2017-02-25 发布日期:2017-12-18
  • 作者简介:于四景（1972-），男，副主任医师。研究方向：小儿传染病的中西医结合治疗，E-mail：yusijing1972@126.com

Analysis of children's hand-foot-mouth disease treated by children's soybean granule combined with ribavirin aerosol

YU Sijing   

  1. Department of Infectious Diseases, Children's Hospital of Hunan Province, Changsha 410007，China
  • Online:2017-02-25 Published:2017-12-18

PDF (PC)

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摘要： 目的:探讨小儿豉翘颗粒联合利巴韦林气雾剂治疗手足口病的临床治疗效果。
方法:选择2015年2月至2016年2月湖南省儿童医院感染科收治的手足口病患儿78例，随机分为观察组和对照组各39例。对照组采用利巴韦林气雾剂治疗，观察组在对照组治疗基础上联合小儿豉翘颗粒治疗。治疗7 d后，观察两组治疗效果、症状体征消失时间及不良反应情况。
结果:观察组总有效率为97.44%（38/39），显著高于对照组74.36%（29/39），差异有统计学意义（P<0.05）。观察组患儿退热时间、皮疹消退时间和痊愈时间均短于对照组，差异有统计学意义（P<0.05）。观察组患儿不良反应发生率为2.56%（1/39），显著低于对照组23.08%（9/39），差异有统计学意义（P<0.05）。
结论:采用小儿豉翘颗粒联合利巴韦林气雾剂临床治疗小儿手足口病，具有较高的疗效，并且临床不良反应发生率较低，安全性很高，用药较为方便简单，因而可将其广泛地推广至临床治疗中。

关键词: 手足口病, 小儿豉翘颗粒, 利巴韦林气雾剂, 疗效分析, 儿童

Abstract: Objective:To explore the clinical effect of soybean granule combined with ribavirin aerosol for children with hand-foot-mouth disease(HFMD).
Methods:A total of 78 children with HFMD, who were treated in our hospital from February 2015 to February 2016, were randomly divided into observation group and control group(39 cases in each group). The patients in the control group were treated with aerosolized ribavirin. The patients in the observation group were treated with the combination of children's soybean granules and ribavirin aerosol. Seven days after treatment, the effect in the two groups of pediatric patients, the corresponding clinical signs and symptoms and the adverse reactions were compared.
Results:The total effective rate was 97.44% in the observation group and 82.05% in the control group. The total effective rate in the observation group was significantly higher than that in the control group(P<0.05). The time of fever subsidence, the time of rash disappearance and the recovery time were shorter in the observation group than in the control group. There was significant difference between the two groups (P<0.05). The adverse reaction rate was 2.56% in the observation group and 23.08% in the control group. There was a significant difference between the two groups(P<0.05).
Conclusion:The treatment for pediatric hand-foot-mouth disease with the combination of pediatric soybean granules and ribavirin aerosol have a high efficacy and a low incidence of clinical adverse reactions, with high safety and convenient and simple administration. It should be promoted in clinical treatment.

Key words: Hand-foot-mouth disease, Pediatric soybeans granule, Ribavirin aerosol, Curative effect analysis, Children