关键词: 性早熟, 性早熟年龄, 中枢性性早熟, GnRH激发试验, 儿童

Abstract: Objective：To investigate the status of patients with precocious puberty in Chinese cities，and provide a theoretical basis for making effective prevention strategy，and promoting clinical standardization and personalized treatment of precocious puberty.
Methods："Precocious Puberty Research in Chinese cities" activities began in the period between March and December 2014.Among a total of 2 687 questionnaires，1 714 were included in the final statistical analysis.
Results：The survey of patients with city distribution were mainly in 10 cities，the top three being Chongqing(21.28%)，Changzhou(9.26%) and Shanghai(8.37%).Girls dominated the survey，and male to female ratio was about 1∶16;In secondary inspection，patients diagnosed with central precocious puberty accounted for 75.79% by GnRH stimulation test.Initial diagnosis of patients with central precocious puberty accounted for 88.91%.In all patients with central precocious puberty，bone age was higher than the actual average age at about 1.65 years old and the differences were statistically significant（P＜0.001）.
Conclusion：The patients with central precocious puberty in Chinese cities are generally older. In order to avoid missing the best time for intervention and treatment，great importance should be attached to the disease screening，and early detection，early diagnosis and early treatment must be done.

Key words: Precocious puberty, Precocious age, Central precocious puberty, GnRH stimulation test, Children