ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2015, Vol. 7 ›› Issue (6): 581-583.doi: 10.3969/j.issn.1674-3865.2015.06.016

• 临床研究 • 上一篇    下一篇

沙丁胺醇联合醒脾养儿颗粒治疗儿童夜遗尿疗效观察

郭翠翠，吕学云，张玉琨，杨巧芝   

  1. 252000 山东 聊城，泰山医学院聊城临床学院研究生处（郭翠翠）；聊城市儿童医院小儿内科（吕学云，张玉琨，杨巧芝）
  • 出版日期:2015-12-25 发布日期:2018-11-19
  • 通讯作者: 杨巧芝，E-mail:sdlcyqz001@163.com
  • 作者简介:郭翠翠（1988-），女，泰山医学院聊城临床学院2012级硕士研究生。研究方向：小儿肾脏病的诊治

Clinical study on salbutamol combined with Xingpi Yanger particles in treatment of children with nocturnal enuresis

GUO Cuicui, LYU Xueyun,ZHANG Yukun,YANG Qiaozhi   

  1. Liaocheng People's Hospital of Taishan Medical College, Liaocheng 252000，China.
  • Online:2015-12-25 Published:2018-11-19

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摘要：
目的: 观察沙丁胺醇联合醒脾养儿颗粒治疗儿童原发性夜遗尿的临床疗效。
方法: 2013-07/2014-09聊城市儿童医院遗尿专科门诊收治78例原发性夜遗尿患儿，随机分为中药组26例和中西药组52例。两组均结合心理行为疗法，中药组给予醒脾养儿颗粒治疗，治疗2个月；中西药组在服用醒脾养儿颗粒的基础上，加用硫酸沙丁胺醇片口服，治疗2个月。对两组患儿在治疗结束时(近期)及治疗结束后3个月(远期)评估其疗效并进行分析。
结果: 中西药组近期及远期总有效率分别为86.6%（45/52）、82.7%（43/52），均高于中药组65.4%（17/26）、61.6%（16/26），差异有统计学意义(P<0.05)；两组复发率比较差异无统计学意义(P＞0.05)。
结论: 沙丁胺醇联合醒脾养儿颗粒治疗儿童夜遗尿起效快，停药后复发率低，疗效肯定，值得临床推广。

关键词: 遗尿症, 沙丁胺醇, 治疗应用, 醒脾养儿颗粒, 治疗应用, 儿童

Abstract:
Objective：To observe the clinical curative effects of salbutamol and Xingpiyanger particles on children with primary nocturnal enuresis.
Methods：Totally 78 patients with primary nocturnal enuresis who accepted the treatment for 2 months were randomized into two groups: Chinese medicine group (Xingpiyanger particles), Chinese and western medicine group(Xingpiyanger particles + salbutamol). Both two groups also received psychologicalbehavioral therapy. The curative effect in the two groups was evaluated at the end of the treatment and 3 months after the treatment and statistical analysis was performed.
Results：The total effective rate in Chinese and western medicine group was superior to Chinese medicine group at the end of the treatment and 3 months after the treatment (P=0.029 and 0.04), the difference being statistically significant. There was no significant difference in relapse rate between two groups.
Conclusion：The clinical curative effects of salbutamol and Xingpiyanger particles in children with primary nocturnal enuresis are relatively high with lower relapse rate. So, it is worth clinical promotion in treating PNE in China.

Key words: Nocturnal enuresis, Salbutamol, therapeutic use, Xingpi Yanger particles, therapeutic use, Children