关键词: 过敏性紫癜, 中西医结合, 三黄清血饮, 儿童

Abstract:
Objective
To investigate and analyze the clinical efficacy and safety of integrated traditional Chinese and Western medicine in the treatment of allergic purpura in children.
Methods
A total of 58 children with allergic purpura were selected in our hospital from June 2012 to December 2016, and randomly divided into two groups. The 29 cases simply treated with western medicine were as control group, and 29 cases treated with integrated traditional Chinese and western medicine were as observation group. The control group received intravenous drip of Cimetidine injection at 40 mg/(kg.d), once a day; oral Loratadine Syrup was also used at 5 mL each time, once a day. The course of treatment was 1 to 2 weeks. Besides the treatment for control group, the observation group was given Sanhuang Qingxue Yin, one dose a day, to be taken separately in the morning and evening, which lasted for 1 to 2 courses, one week as a course. The clinical efficacy, time for symptoms to disappear and the complications during treatment of the two groups were compared.
Results
The total effective rate of the observation group was 96.5%(28/29), which was significantly higher than that of the control group(69.0%,20/29)(P<0.05). The time for swelling pain, rash and digestive tract symptoms to disappear in the observation  group was shorter than that in the control group(P<0.05).Kidney damage occurred in both groups, but the incidence of complications in both groups was not statistically difference(P>0.05).
Conclusion
The treatment for children with allergic purpura by combination of Sanhuang Qingxue Yin can effectively improve the clinical efficacy.

Key words: Allergic purpura, Integrative traditional Chinese and western medicine therapy, Sanhuang Qingxue Yin, Children