Abstract:
Objective
To understand the epidemiological characteristics of Henoch-Schonlein purpura(HSP) in children, observe the prognosis of children with HSP, and analyze the risk factors of long-term urinary abnormalities in children with HSP.
Methods
Collect and retrospectively analyze the clinical data and feedback of hospitalized children diagnosed with HSP in the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine from October 2010 to September 2017.
Results
Respiratory tract infection is the leading cause of the onset of HSP in children. Skin purpura is the first symptom of HSP in 502/542(92.62%) children, and 15.13%(82/542) hospitalized children had kidney damage; 21.34%(89/417) children had HSP recurrence. The long-term urinary routine was closed related to kidney type of in-hospital diagnosis(OR =4.589, 95%CI 2.357-8.934), children's age at onset being greater than or equal to 6 years old(OR =2.113, 95%CI 1.094-4.079) and recurrent purpura(OR=2.403, 95%CI 1.249-4.622).
Conclusion
The children with HSP are prone to recurrent skin purpura, and hospitalized children with kidney damage are prone to recurrence(P=0.006<0.05); long-term abnormal routine urine is related to the kidney type of in-hospital diagnosis, onset age ≥6 and recurrent purpura, but is not related to the in-hospital diagnosis of abdominal purpura(P >0.05).

Key words: Purpura, Allergy, Renal damage, Long-term prognosis, Children