ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (1): 62-64.doi: 10.3969/j.issn.1674-3865.2016.01.023

• 临床研究 • 上一篇    下一篇

酚妥拉明佐治婴幼儿腹泻致小儿肠梗阻疗效观察

梁殿哲   

  1. 733000 甘肃 武威，武威市凉州医院儿科
  • 出版日期:2016-02-25 发布日期:2018-11-19
  • 作者简介:梁殿哲(1973-)，男，副主任医师。研究方向：中西医结合治疗小儿消化系统疾病，E-mail：ldz13809351762@163.com

Effect of phentolamine in the treatment of pediatric intestinal obstruction caused by diarrheaLIANG Dianzhe

LIANG Dianzhe   

  1. Department of Pediatrics，Wuwei Liangzhou Hospital，Wuwei 733000，China
  • Online:2016-02-25 Published:2018-11-19

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摘要：
目的：观察酚妥拉明佐治小儿(不完全性)肠梗阻的临床疗效。
方法：武威市凉州医院儿科2012年6月至2015年6月收治80例确诊为(不完全)肠梗阻的住院患儿，随机分为对照组和观察组各40例。对照组给予禁食水、胃肠减压、补液、灌肠等综合治疗，观察组在此治疗基础上加用酚妥拉明，观察两组病例治疗后临床症状改善情况及恢复时间。
结果：观察组48 h、72 h、4～6 d治愈率分别为37.5%(15/40)、95.0%(38/40)、100.0%(40/40)，对照组分别为20.0%(8/40)、70.0%(28/40)、82.5%(33/40)。观察组在治疗72 h和4～6 d的治愈率显著高于对照组，差异有统计学意义(P＜0.05)。
结论：酚妥拉明佐治小儿(不完全性)肠梗阻在临床症状恢复及缩短病程方面明显高于对照组，且安全有效，值得在儿科临床上推广应用。

关键词: 肠梗阻, 酚妥拉明, 保守治疗, 儿童

Abstract:
Objective：To observe the effect of phentolamine in the treatment of children with (incomplete) intestinal obstruction.
Methods：Eighty children with (incomplete) intestinal obstruction hospitalized in the Pediatric Department of Wuwei Liangzhou Hospital form June 2012 to June 2015，were randomly divided into control group(n=40) and treatment group(n=40).The control group was given water fasting，gastrointestinal decompression，rehydration，enema and other comprehensive treatment，and for the treatment group，on the basis of the treatment for control group，phentolamine was given;observe clinical symptoms improvement and recovery time after treatment in the two groups.
Results：The cure rate of the treatment group(48 h，72 h，4～6 d) was 37.5%（15/40），95.0%（38/40） and 100.0%（40/40） respectively，while in the control group it was 20.0%（8/40），70.0%（28/40） and 82.5%（33/40）.The cure rate at 72 h and 4～6 days in treatment group was significantly higher than that in the control group，the difference being statistically significant(P＜0.05).
Conclusion：Phentolamine is effective in improving in clinical symptoms and shortening the course of the disease in the treatment of children with (incomplete) intestinal obstruction，which is worthy of popularied and applied in pediatric clinics，and it is safe and effective.

Key words: Intestinal obstruction, Phentolamine, Conservative treatment, Children