ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (1): 67-69.doi: 10.3969/j.issn.1674-3865.2016.01.025

• 临床研究 • 上一篇    下一篇

中药泻火解毒汤治疗大叶性肺炎疗效观察

林昱   

  1. 115000 辽宁 营口，营口市中医院儿科
  • 出版日期:2016-02-25 发布日期:2018-11-19
  • 作者简介:林昱(1973-)，女，副主任医师。研究方向：小儿呼吸系统疾病的诊治，E-mail：15504171059@163.com

Clinical observation on treatment for lobar pneumonia with Xiehuo Jiedu decoction

LIN Yu   

  1. Yingkou Hospital of Traditional Chinese Medicine，Yingkou 115000，China.
  • Online:2016-02-25 Published:2018-11-19

PDF (PC)

93

摘要：
目的：观察口服中药泻火解毒汤治疗小儿大叶性肺炎的临床疗效。
方法：营口市中医院儿科2013年1月1日至12月31日收治大叶性肺炎患儿382例，随机分为观察组与对照组各191例。对照组采用单纯西医抗感染治疗；观察组在对照组治疗基础上予中药泻火解毒汤口服，每日1剂，每日2次，每次口服15～40 mL，疗程2周，疗程结束后观察临床疗效、治疗前后体内C反应蛋白水平以及其他临床症状缓解消失时间。
结果：观察组总有效率为96.3%(184/191)，显著高于对照组71.2%(136/191)，差异有统计学意义(P＜0.01)；两组治疗后血清C反应蛋白水平较治疗前均有明显下降，观察组C反应蛋白水平较对照组下降更显著，差异有统计学意义(P＜0.01)。观察组退热时间、抗生素使用时间、住院时间均显著少于对照组，差异有统计学意义(P＜0.01)。
结论：口服中药泻火解毒汤治疗小儿大叶性肺炎可显著降低其机体C反应蛋白水平，缩短退热所需时间、抗生素使用时间、住院时间，进而提高临床疗效，值得临床推广应用。

关键词: 肺炎, 肺炎球菌性, 泻火解毒汤, 临床观察, 儿童

Abstract:
Objective：To observe the clinical effect of oral Xiehuo Jiedu decoction in the treatment of children with lobar pneumonia.
Methods：A total of 382 cases of lobar pneumonia were selected and randomly divided into two groups：the control group and the treatment group.The control group was given a simple antiinfection treatment of western medicine，while the treatment group was given Xiehuo Jiedu decoction treatment in addition to the western treatment，one dose daily，twice a day，about 15～40 mL each time，for two weeks as a treatment course.At the end of treatment，observe the clinical efficacy.
ResultsThe total effective rate of the treatment group was 96.3%，and the total effective rate was 71.2% in the control group，showing that the treatment group was significantly better than the control group with statistical difference（P＜0.01）.The serum levels of C reactive protein in the two groups were significantly decreased compared with those before treatment，but the decrease in the treatment group was more obvious than that in the control group，the difference being statistically significant（P＜0.01）.The fever time，antibiotics use time and length of hospital stay in treatment group were significantly less than that of the control group，and the difference had statistical significance(P＜0.01).
Conclusion：In the treatment of infantile lobar pneumonia Xiehuo Jiedu decoction can significantly reduce the C reactive protein level，shorten the time of fever-relieving，antibiotic use and hospital stay，and thus improve the clinical efficacy，which is worthy of clinical application.

Key words: Pneumonia, pneumococcal, Xiehuo Jiedu decoction, Clinical observation, Children