ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (1): 85-87.doi: 10.3969/j.issn.1674-3865.2016.01.031

• 临床研究 • 上一篇    下一篇

50例脑性瘫痪患儿高危因素分析

王春丽，龙旭浩   

  1. 110032 沈阳，辽宁中医药大学研究生学院(王春丽)，辽宁中医药大学附属医院儿科康复中心(龙旭浩)
  • 出版日期:2016-02-25 发布日期:2018-11-19
  • 通讯作者: 龙旭浩，Email：lxhlnzy@163.com
  • 作者简介:王春丽（1989-），女辽宁中医药大学2013级硕士研究生在读。研究方向：小儿脑瘫的诊疗

Analysis of risk factors in children with cerebral palsy

WANG Chunli，LONG Xuhao   

  1. Liaoning University of Traditional Chinese Medicine，Shenyang 110032，China.
  • Online:2016-02-25 Published:2018-11-19

PDF (PC)

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摘要： 目的：分析小儿脑性瘫痪(简称脑瘫)相关高危因素，为预防该病提供参考。
方法：2013年10月至2015年3月辽宁中医药大学附属医院儿科康复中心收治50例脑瘫患儿，为观察组。同期选择100例非脑瘫患儿和健康儿童进行1∶2匹配，为对照组。通过查阅住院病历及询问儿童父母完成问卷调查。调查项目包括妊娠高血压、多胎、早期破水、早产、低体质量、新生儿窒息、颅内出血。数据采用Logistic回归分析。
结果：单因素分析显示，早产、低体质量、多胎、病理性黄疸、新生儿窒息、羊水早破、缺氧缺血性脑病、感染8项指标是发生小儿脑瘫的危险因素，差异有统计学意义(P＜0.05)；多因素分析显示，早产、低体质量、病理性黄疸、新生儿窒息、多胎为小儿脑瘫发病的主要危险因素。
结论：小儿脑瘫病因复杂，做好围产期和分娩期的保健工作是重中之重。

关键词: 脑性瘫痪, 危险因素, 儿童

Abstract: Objective：To analyze the relevant risk factors of cerebral palsy(CP) and provide a reference for the prevention of the disease.
Methods：The 50 children with cerebral palsy hospitalized in Pediatric Rehabilitation Center from October 2013 to March 2015 were studied as observation group.The 100 healthy children were selected as control group.A 1∶2 matched casecontrol study was conducted.Complete the questionnaire by consulting the medical records of the hospital and inquiring the parents of the children.The survey items included pregnancyinduced hypertension，multifetus，premature rupture of the amniotic fluid，premature birth，low weight at birth，neonatal asphyxia and intracranial hemorrhage(ICH).All data were analyzed with Logistic regression.
Results：Oneway analysis showed that premature birth，low weight at birth，multifetus，pathological jaundice，neonatal asphyxia，premature rupture of the amniotic fluid，hypoxicischemic encephalopathy and infection were risk factors for cerebral palsy in children(P＜0.05).The multivariate analysis showed that premature birth，low weight at birth，pathological jaundice，neonatal asphyxia and multifetus were main risk factors.
Conclusion：The relevant risk factors of CP are various，so taking precautious measures during gestation and perinatal period is important.

Key words: Cerebral palsy, Risk factors, Children