ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (2): 175-177.doi: 10.3969/j.issn.1674-3865.2016.02.016

• 临床研究 • 上一篇    下一篇

复方甘草酸苷注射液治疗小儿肺炎合并肝功能损害疗效观察

杨金玲   

  1. 459000 河南 济源，济源市妇幼保健院儿科
  • 出版日期:2016-04-25 发布日期:2018-11-19
  • 作者简介:杨金玲(1975-)，女，医学硕士，副主任医师。研究方向：小儿呼吸系统疾病的诊治，E-mail：yangjinling2008@126.com

Effect observation of compound glycyrrhizin injection in the treatment of children with pneumonia and liver dysfunction

YANG Jinling   

  1. Women and Children Hospital in Jiyuan City,Jiyuan 459000，China.
  • Online:2016-04-25 Published:2018-11-19

PDF (PC)

102

摘要：
目的：观察复方甘草酸苷注射液辅助治疗小儿肺炎合并肝功能损害的治疗效果。
方法：2014年1月至2015年5月济源市妇幼保健院儿科收治住院的肺炎合并肝功能损害患儿60例，随机分为观察组和对照组各30例。两组肺炎治疗均给予头孢曲松抗感染和雾化吸入治疗，观察组在治疗肝功能损害上给予复方甘草酸苷注射液静脉应用；对照组给予肝泰乐治疗肝功能损害。
结果：观察组总有效率967％(29/30)，显著高于对照组733％(22/30)，差异有统计学意义(P<005)。观察组总疗程为(568±121)d，显著低于对照组(922±098)d，差异有统计学意义(P<005)。两组在治疗过程中血、尿、肾功能均在正常范围，无明显不良反应。
结论：静脉应用复方甘草酸苷注射液协同抗菌药物、雾化吸入治疗小儿肺炎合并肝功能损害，既加快了肺炎的好转，又促进肝功能的恢复。

关键词: 肺炎, 肝功能损害, 复方甘草酸苷注射液, 肝泰乐, 儿童

Abstract:
Objective:To investigate the effect of compound glycyrrhizin injection in the treatment of children with pneumonia and liver dysfunction.
Methods:From January 2014 to May 2015 in Women and Children Hospital in Jiyuan city,60 children admitted to the hospital for pneumonia and liver dysfunction were randomly divided into two groups:the observation group and the control group.Two groups were both given anti-infection and inhalation therapy to treat pneumonia.The observation group was given compound glycyrrhizin injection to cure liver dysfunction,while the control group was given glucurolactone injection.
Results:The total effective rate of observation group was 967%(29/30),significantly higher than the total effective rate of control group［733%(22/30)］,the difference being statistically significant(P<005).The total course of the observation group was(568±121)d,significantly shorter than the control group(922±098)d,the difference being statistically significant(P<005).The result of blood,urine and kidney function of two groups during treatment was in the normal range,with no significant adverse reactions.
Conclusion:The compound glycyrrhizin injection combined with antibacterial drugs and inhalation treatment for children with pneumonia and liver dysfunction has good effect,which can not only accelerate the improvement of pneumonia,but also promote the recovery of liver function.

Key words: Pneumonia, Liver dysfunction, Compound glycyrrhizin injection, Glucurolactone, Children