ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (2): 185-187.doi: 10.3969/j.issn.1674-3865.2016.02.020

• 临床研究 • 上一篇    下一篇

小儿迁延性细菌性支气管炎126例临床分析

李俊玲   

  1. 471200河南 洛阳，河南省汝阳县人民医院儿科
  • 出版日期:2016-04-25 发布日期:2018-11-19
  • 作者简介:李俊玲（1976-），女，主治医师。研究方向：小儿呼吸系统疾病的诊治

Clinical analysis of infantile persistent bacterial bronchitis in 126 cases

LI Junling   

  1. Department of Pediatrics，Ruyang County People′s Hospital,Luoyang 471200，China.
  • Online:2016-04-25 Published:2018-11-19

PDF (PC)

126

摘要：
目的：分析小儿迁延性细菌性支气管炎的临床特征。
方法：2010年2月至2015年3月河南省汝阳县人民医院儿科收治住院的支气管炎患儿126例，均给予抗生素治疗。分析其临床特点及治疗效果。
结果：126例中主要临床表现为持续性咳嗽，可闻及湿啰音；其中伴有喘息者91例(722%)；时相分布表现为昼夜无规律性；咳嗽时间平均为(47±03)周。纤维支气管镜下可见气管黏膜水肿、充血，其中合并气道软化48例(381%)；实验室检查显示CD3-CD16+比例升高；肺泡灌洗液细菌培养阳性率为365%(46/126)，主要致病菌为流感嗜血杆菌和肺炎链球菌；中性粒细胞升高706%(89/126)。给予三代头孢菌素或阿莫西林克拉维酸治疗后，患儿预后良好，平均治疗时间(154±36)d。
结论：小儿迁延性细菌性支气管炎临床主要特征为持续性可伴有湿啰音的咳嗽，部分患儿存在喘息症状，并可伴气道软化。主要致病菌为流感嗜血杆菌和肺炎链球菌。积极抗生素治疗可获得良好效果。

关键词: 细菌性支气管炎, 临床特征, 治疗, 儿童

Abstract:
Objective:To investigate the clinical features of infantile persistent bacterial bronchitis.
Methods:Totally 126 cases were selected and treated with antibiotics in the Department of Pediatrics in People′s Hospital of Ruyang County from February 2010 to March 2015,and the clinical characteristics and treatment effect were analyzed.
Results:The main clinical manifestations were persistent cough,and roles could be heard;among the 126 cases,91 cases (722%) were accompanied by wheezing;it was not regular during day and night;the mean time of cough was (47±03) weeks.Edema and congestion of tracheal mucosa were observed under the microscope,and 48 cases(381%) were with airway softening.Laboratory tests showed that the proportion of CD3-CD16+ increased.The positive rate of bacterial culture in bronchoalveolar lavage fluid was 365% (46/126).The main pathogens were Haemophilus influenzae and Streptococcus pneumonia,and neutrophil elevation was 706%(89/126).The patients had good prognosis after treatment with the third generation cephalosporin or amoxicillin clavulanate,the average treatment time (154±36)d.
Conclusion:The main clinical features of infantile persistent bacterial bronchitis are persistent cough with moist rales,and some children have wheezing symptoms,which can be accompanied by airway softening.The main pathogens are Haemophilus influenzae and Streptococcus pneumoniae.Positive antibiotic treatment can produce better therapeutic effect.

Key words: Bacterial bronchitis, Clinical features, Treatment, Children