ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (2): 200-202.doi: 10.3969/j.issn.1674-3865.2016.02.026

• 临床研究 • 上一篇    下一篇

万托林与普米克联合雾化治疗小儿哮喘疗效观察

汪宜文，张孔良，刘湘玉，徐海明   

  1. 518109 深圳，深圳市龙华新区人民医院儿科
  • 出版日期:2016-04-25 发布日期:2018-11-19
  • 通讯作者: 张孔良，E-mail：yaok2013@163.com
  • 作者简介:汪宜文(1965-)，男，主治医师。研究方向：婴幼儿哮喘的诊治

Observation of curative effect of the treatment of asthma in children with ventolin and Pulmicort aerosol for children with asthma

WANG Yiwen，ZHANG Kongliang，LIU Xiangyu，XU Haiming   

  1. Department of Pediatrics，People's Hospital of Longhua New District，Shenzhen 518109，China.
  • Online:2016-04-25 Published:2018-11-19

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138

摘要：
目的：观察万托林与普米克联合雾化治疗小儿哮喘的治疗效果。
方法：深圳市龙华新区人民医院儿科2014年1月至2015年1月收治哮喘患儿90例，随机分为观察组与对照组各45例。对照组患儿单纯应用普米克治疗，观察组在此基础上应用万托林治疗，3 d为1个疗程。观察两组治疗效果及治疗前后肺功能水平的变化，观察两组患儿用药治疗期间的不良反应。
结果：观察组治疗总有效率为97.8%(44/45)，显著高于对照组82.2%(37/45)，差异有统计学意义(P＜0.05)。观察组治疗后用力肺活量(FVC)、一秒用力呼气容积(FEV1)、呼气流速峰值(PEF)水平显著高于对照组，差异有统计学意义(P＜0.05)。两组患儿用药期间均未出现药物不良反应。
结论：万托林与普米克联合雾化治疗小儿哮喘疗效显著，可有效改善患儿的临床症状与体征，强化肺功能水平，安全可靠。

关键词: 哮喘, 万托林, 普米克, 雾化治疗, 儿童

Abstract:
Objective:To observe the curative effect of the treatment with ventolin and Pulmicort aerosol for children with asthma.
Methods:Totally 90 cases of children with asthma treated in our hospital from January 2014 to January 2015 were selected and randomly divided into the observation group and the control group，45 cases in each group.The children in control group were only treated with Pulmicort，while children in the observation group were treated with ventolin based on the therapy of the control group，three days as a course.The therapeutic effects of the two groups and the changes in the level of pulmonary function were observed before and after treatment，and the adverse reactions of two groups during the treatment were also observed.
Results:The total effective rate of the observation group was 97.8%(44/45)，which was significantly higher than that ［82.2%(37/45)］ in the control group.The differences were statistically significant(P＜0.05).After treatment，the forced vital capacity(FVC)，forced expiratory volume in one second(FEV1) and peak expiratory flow(PEF) levels in patients in the observation group were significantly higher than those in the control group，and the differences had statistical significance(P＜0.05).There was no adverse drug reaction in the two groups during medication period.
Conclusion:The treatment for children with asthma with ventolin and Pulmicort aerosol is significant.This treatment method can effectively improve the patient's clinical symptoms and signs and strengthen the level of pulmonary function，which is safe and reliable.

Key words: Asthma, Ventolin aerosol, Pulmicort, Atomization treatment, Children