ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (3): 301-303.doi: 10.3969/j.issn.1674-3865.2016.03.017

• 临床研究 • 上一篇    下一篇

中医康复理疗结合肉毒毒素A注射治疗小儿脑性瘫痪的临床观察

吴值荣，马彩云，尚清，张继华   

  1. 450000 郑州，郑州市儿童医院康复医学科
  • 出版日期:2016-06-25 发布日期:2018-11-19
  • 通讯作者: 马彩云，E-mail：mcyun126@126.com
  • 作者简介:吴值荣(1982-)，女，医学硕士，医师。研究方向：小儿神经系统疾病的诊治

Clinical effect of rehabilitation therapy of Chinese medicine combined with botulinum toxin A in children with cerebral palsy

WU Zhirong，MA Caiyun，SHANG Qing，ZHANG Jihua   

  1. Department of Rehabilitation Medicine,Children′s Hospital of Zhengzhou,Zhengzhou 450000,China.
  • Online:2016-06-25 Published:2018-11-19

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摘要：
目的: 观察中医康复理疗结合肉毒毒素A注射治疗小儿脑性瘫痪(简称脑瘫)的临床疗效。
方法: 2013年3月至2015年3月郑州市儿童医院康复中心收治住院的脑瘫患儿80例，随机分为观察组和对照组各40例。对照组给予中医康复理疗，观察组给予中医康复理疗联合肉毒毒素A注射治疗。治疗6个月后观察两组治疗效果。
结果: 观察组治疗后总有效率为82.5%(33/40)，显著高于对照组的62.5%(25/40)，差异有统计学意义(P<0.05)。观察组治疗结束后3个月患者痉挛程度评分为(2.74±0.36)分，显著低于对照组(3.85±0.33)分，差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。
结论: 中医康复理疗联合肉毒毒素A注射治疗小儿脑瘫临床疗效显著，可改善患儿认知功能，对提高患儿生活质量意义重大。

关键词: 脑性瘫痪, 中医康复理疗, 肉毒毒素A, 临床疗效, 儿童

Abstract:
Objective: To study the clinical effect of rehabilitation therapy of Chinese medicine combined with botulinum toxin A in children with cerebral palsy.
Methods: From Mar.2013 to Mar.2015,a total of 80 cerebral palsy children who accepted treatments in our hospital were taken as the clinical research objects,and these patients were randomly divided into observation group (40 cases) and control group (40 cases).Patients in the control group were given rehabilitation therapy of Chinese medicine,and the other patients in the observation group were given rehabilitation therapy of Chinese medicine combined with botulinum toxin A.Six months after treatments,we observed and compared the clinical effects in these two groups.
Results: The total effective rate of the observation group was 82.5%(33/40)，which was significantly higher than that of the control group 62.5%(25/40),and the difference was statistically significant(P<0.05).Three months after the end of the treatment,the spasm score was (2.74±0.36) in the observation group,which was significantly lower than that of the control group(3.85±0.33),and the difference was statistical(P<0.05).The incidence of adverse reaction had no statistical difference between the two groups.
Conclusion: Rehabilitation therapy of Chinese medicine combined with botulinum toxin A can improve children′s cognitive function and life quality,which has remarkable effect in the treatment of cerebral palsy.

Key words: Cerebral palsy, Rehabilitation therapy of Chinese medicine, Botulinum toxin A, Clinical effect, Children