腹泻病婴幼儿艰难梭菌定植与感染情况分析

doi:10.3969/j.issn.1674-3865.2016.06.019

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (6): 607-609.doi: 10.3969/j.issn.1674-3865.2016.06.019

腹泻病婴幼儿艰难梭菌定植与感染情况分析

郭亚楠，王君，李佳垚，王秋萍，刘欣竹

100029 北京，中日友好医院儿科(郭亚楠，王君，王秋萍，刘欣竹)；100073 北京，北京协和医院检验科(李佳垚)

出版日期:2016-12-25 发布日期:2018-11-19
通讯作者: 王君，E-mail：junw20042003@qq.com
作者简介:郭亚楠(1989-)，男，硕士研究生。研究方向：中医药治疗儿科疾病

The analysis of clostridium difficile colonization and infection in infants with diarrhea

GUO Yanan,WANG Jun,LI Jiayao，WANG Qiuping，LIU Xinzhu

China-Japan Friendship Hospital, Beijing 100029，China

Online:2016-12-25 Published:2018-11-19

摘要/Abstract

摘要： 目的：了解腹泻病婴幼儿艰难梭菌定植与感染情况并探讨其检测方法。
方法：收集2014~2015年儿科消化门诊腹泻婴幼儿的临床资料及粪便，通过厌氧培养、毒素A和B PCR扩增法和酶联免疫法检测粪便中艰难梭菌和毒素。
结果：65份标本中，厌氧培养阳性19例(29.23%)，19例经PCR扩增，A/B毒素阳性5例(7.69%)；酶联免疫法检测抗原阳性22例(33.85%)，与厌氧培养比较，差异无统计学意义（P＞0.05），毒素A/B阳性5例(7.69%)与PCR扩增法比较，差异无统计学意义（P＞0.05）。
结论：婴幼儿有较高的艰难梭菌定植率，其中多为非产毒株，并不致病；酶联免疫法检测艰难梭菌抗原和毒素可以用于临床筛检。

关键词: 腹泻, 艰难梭菌, 婴幼儿

Abstract:

Objective;To analyze the assessment results analysis of the universality and specificity of the life quality questionnaire for CA children.
Methods
A total of 42 CA children who were confirmed in Shenyang Children's Hospital from Jan. to Dec. 2015 were chosen as the CA group, and 45 children who were disgnosed with upper respiratory tract infection in the same period were included as the control group. Both groups of children were assessed by univesality and specificity of life quality questionnaire.
Results;In the assessment of univesality of life quality questionnaire, the factor score on peer relationship, school life, depression experience, anxiety experience and body experience and the total satisfaction score were both lower in CA group than those in control group (P＜0.05). In the assessment of specificity of life quality questionnaire, the factor score on asthmatic symproms, limited movement, reaction to stimulation, psychological state and attention to their own health and AQLQ total score were significantly higher in CA group than those in control group (P＜0.05).
Conclusion;The present situation of universality and specificity of life quality is not very good.

Key words: Asthma；Specific life quality/AQLQ for children；Universal life quality/subjective life quality questionnaire for children, Children

郭亚楠，王君，李佳垚，王秋萍，刘欣竹. 腹泻病婴幼儿艰难梭菌定植与感染情况分析[J]. 中国中西医结合儿科学, 2016, 8(6): 607-609.

GUO Yanan,WANG Jun,LI Jiayao，WANG Qiuping，LIU Xinzhu. The analysis of clostridium difficile colonization and infection in infants with diarrhea[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2016, 8(6): 607-609.

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腹泻病婴幼儿艰难梭菌定植与感染情况分析

The analysis of clostridium difficile colonization and infection in infants with diarrhea

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