关键词: 重症水痘, 病因, 实验室检查, 治疗, 儿童

Abstract:
Objective
To explore the clinical characteristics of children's intensive chicken pox and its effective treatment method,providing the basis for clinical work.
Methods
A total of 98 children with intensive chicken pox were chosen,who were treated in Hunan Children's Hospital from Feb. 2015 to Feb. 2017,and their clinical data were analyzed.
Results
(1)Cause analysis:about 91.84%(90/98) children had contact with children with chicken pox;about 6.12%(6/98) children had contact with children with herpes zoster,2.04%（2/98） with unknown cause. (2) Clinical manifestations:all the 98 cases of children had a high fever,fatigue and sleepiness,including skin sores(68.37%,67/98),gastrointestinal(57.14%,56/98),cough（66.33%，65/98),muscle pain(20.41%,20/98),tic(11.22%,11/98),palpebral conjunctiva herpes(59.18%,58/98),oral herpes(43.88%,43/98) and genital herpes (27.55%,27/98).(3)Laboratory results:white blood cell count,neutrophil percentage and number of platelets were decreased obviously,while lymphocyte percentage,C-reactive protein,lactate dehydrogenase,aspartate transaminase,serum creatinine and blood urea nitrogen content were higher. (4) Complications:94.90%(93/98) of the children had pulmonary bacterial infections;liver injury occurred in 91.84%(90/98) of the children,encephalitis in 83.67%(82/98), thrombocytopenia in 54.08%(53/98),and myocarditis in 42.86%(42/98). (5) Prognosis:Two out of 98 children died due to long-term use of glucocorticoid and reduced platelet,which resulted in multiple organ failure,while the other 96 children recovered.
Conclusion
The condition of intensive chicken pox is relatively complex;in addition to high fever,fatigue and sleepiness,skin sores and cough are the most common clinical manifestations,which often involves the liver and lungs;treatment should focus on proper medication and be alert to the occurrence of complications.

Key words: Intensive chicken pox, Etiology, Laboratory examination, Treatment, Children